Getting The Most From Your Treatment
- Sometimes people taking medicines like amantadine can fall asleep suddenly with little or no warning of being tired beforehand. Until you know how you react, take extra care if you operate machinery or drive. If you do find yourself falling asleep suddenly, you should see your doctor as soon as possible for advice, and avoid driving or using tools and machines in the meantime.
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How Should I Take Symmetrel
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
If you take amantadine to treat influenza A, start taking the medicine within 24 to 48 hours after flu symptoms begin. Keep taking amantadine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.
If you take this medicine for Parkinson symptoms, your doctor may occasionally change your dose to make sure you get the best results.
Amantadine will not treat an infection caused by bacteria. Call your doctor if your symptoms do not improve, or if you have a fever with a headache, cough, skin rash, or other new symptoms.
If you take amantadine for Parkinson symptoms: You should not stop using amantadine suddenly or your condition may become worse.
Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.
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Some Side Effects Can Be Serious If You Experience Any Of These Symptoms Call Your Doctor Immediately:
- believing things that are not true
- not trusting others or feeling that others want to hurt you
- lack of interest, enthusiasm, or concern
- dizziness, lightheadedness, fainting, or blurred vision
- swelling of the hands, feet, ankles, or lower legs
- difficulty urinating
- shortness of breath
Amantadine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s MedWatch Adverse Event Reporting program online or by phone .
What You Need To Know About Amantadine For Parkinson Disease
This guide includes everything you need to know about amantadine for the treatment of Parkinson disease and drug-induced extrapyramidal reactions in adults.
In February 2018, the FDA approved amantadine for the treatment of Parkinson disease and drug-induced extrapyramidal reactions in adults.1
Parkinson disease is a neurological disorder where patients have a lack of dopaminergic neurons in the substantia nigra. The affected population is estimated to extend toward 10 million worldwide.2 Drug-induced extrapyramidal reactions, mainly caused by antipsychotics, has led to many problematic symptoms such as dystonia, pseudo-parkinsonism, akathisia, and tardive dyskinesia. Anticholinergics, such as amantadine have been used to treat extrapyramidal symptoms caused by antipsychotics for many years now.3
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What Happens If I Overdose
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amantadine can be fatal.
Overdose symptoms may include fever, aggression, behavior changes, hallucinations, severe headache or pounding in your ears, muscle stiffness, problems with balance or walking, fast heart rate, urinating less than usual, trouble breathing, seizure , or fainting.
What Should I Know About Storage And Disposal Of This Medication
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture .
It is important to keep all medication out of sight and reach of children as many containers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location â one that is up and away and out of their sight and reach.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website for more information if you do not have access to a take-back program.
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How Should This Medicine Be Used
Amantadine comes as a capsule, extended-release capsule , tablet, extended-release tablet , and liquid to take by mouth. The capsules, tablets, and liquid medications are usually taken once or twice a day. The extended-release capsules are usually taken once a day at bedtime. The extended-release tablets are usually taken once a day in the morning. Take amantadine at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take amantadine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the extended-release capsules and extended-release tablets whole do not split, chew, or crush them. If you have difficulty swallowing the extended-release capsule, you may open the capsule and sprinkle the entire contents on a teaspoonful of soft food, like applesauce. Eat the mixture right away and swallow without chewing.
If you are taking amantadine for Parkinson’s disease, your doctor may start you on a low dose of amantadine and gradually increase your dose.
Do not stop taking amantadine without talking to your doctor. If you suddenly stop taking amantadine, you may experience fever, confusion, changes in mental state, or severe muscle stiffness. Your doctor will probably decrease your dose gradually.
Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.
What Should I Do If I Forget A Dose
If you are taking the capsules, tablets, or liquid, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
If you are taking the extended-release capsules or the extended-release tablets, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have forgotten to take the extended-release capsules or extended-release tablets for several days, call your doctor.
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Symmetrel For Parkinson’s Disease
OverviewSymmetrel is a prescription medication approved by the Food and Drug Administration in 1976 for treating motor symptoms associated with all forms of Parkinsonism. Symmetrel is sometimes prescribed to treat dyskinesia in people who are taking Levodopa/Carbidopa. Symmetrel is also known by its drug name, amantadine.
Symmetrel is not suitable for use by people who are allergic to amantadine. Symmetrel should be used with caution in people with glaucoma, mental illness, depression, a history of seizures, low blood pressure, frequent rashes, or problems with the liver, kidney, or heart. Symmetrel may not be appropriate for women who are pregnant or breastfeeding.
Symmetrel is classified as an antiviral and anti-Parkinsonian drug. It is believed that Symmetrel works by increasing the amount of dopamine available in the brain.
How do I take it?Symmetrel is taken orally as a capsule or liquid once or twice a day. Take Symmetrel with food or milk. The best times to take Symmetrel are usually in the morning and at mid-day in order to avoid disrupting sleep.
Avoid alcohol while taking Symmetrel.
Always follow your doctors instructions exactly when taking Symmetrel.
ResultsA 2003 article reviewed the evidence from six clinical trials of amantadine as treatment for Parkinsonism. The trials involved a total of 215 participants. Researchers concluded that there is insufficient data supporting the efficacy and safety of amantadine as a Parkinsons medication.
What Should I Avoid While Taking Symmetrel
Do not receive a “live” nasal flu vaccine while using amantadine, and for at least 48 hours after you stop taking amantadine. The vaccine may not work as well during this time, and may not fully protect you from disease.
Amantadine can cause side effects that may impair your vision, thinking, or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Drinking alcohol with this medicine can cause side effects.
Avoid taking diet pills, caffeine pills, or other stimulants without your doctor’s advice. Taking a stimulant together with amantadine can increase your risk of unpleasant side effects.
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Symmetrel For Multiple Sclerosis
OverviewSymmetrel is a prescription medication approved by the U.S. Food and Drug Administration for treating Parkinsons disease and some types of influenza. It has also demonstrated effectiveness in relieving fatigue in people who have all types of multiple sclerosis . Symmetrel is also known by its drug name amantadine.
Symmetrel is not suitable for use by people who are allergic to rimantadine or who have a certain type of glaucoma, an eye disease.
Symmetrel is classified as an antiviral and anti-Parkinsonian drug. It is unknown how it acts to decrease fatigue in those with MS.
How do I take it?Symmetrel is taken orally with food or milk twice a day, usually in the morning and at midday in order to avoid disrupting sleep. Avoid alcohol while taking Symmetrel.
Always follow your doctors instructions exactly when taking Symmetrel.
Side effectsCommon side effects of Symmetrel include nervousness, dry mouth or nose, sleep disturbance, dizziness, loss of balance, blurred vision and a blotchy rash on the legs.
Rare but serious side effects of Symmetrel include suicidal thoughts or behavior, seizures, neuroleptic malignant syndrome, kidney and liver disease, and melanoma.
Seek medical help immediately if you experience symptoms of an allergic reaction such as trouble breathing, severe dizziness, a rash, or itching or swelling of the face, tongue and throat.
For more information about this treatment, visit:
Symmetrel RxList
How To Use Symmetrel Capsule
Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. If you are taking this medication twice a day and have trouble sleeping after taking it, take the second dose several hours before bedtime.
If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
Dosage is based on your medical condition and response to therapy. In children, the dosage is also based on body weight. Do not take more than prescribed by your doctor.
This medication works best when the amount of medicine in your body is kept at a constant level. Take this medication at evenly spaced intervals throughout the day and night.
If you are taking amantadine for a viral infection, begin taking it as soon as possible. Continue taking it until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a relapse of the infection.
In Parkinson’s disease, the effects of the medication may not be noticed for several weeks. Do not suddenly stop taking the medication because symptoms or side effects may worsen. Your doctor may want to reduce your dose gradually. This medication may not work as well after it has been taken for several months. Tell your doctor if this medication stops working well.
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What Should I Discuss With My Healthcare Provider Before Taking Symmetrel
You should not use amantadine if you are allergic to it, or:
-
if you have received a nasal flu vaccine within the past 14 days.
To make sure amantadine is safe for you, tell your doctor if you have:
-
epilepsy or other seizure disorder
-
congestive heart failure
-
a history of alcoholism or drug addiction or
-
a history of mental illness, psychosis, or suicidal thoughts or actions.
Older adults may be more sensitive to the effects of this medicine.
You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.
People with Parkinson’s disease may have a higher risk of skin cancer . Talk to your doctor about this risk and what skin symptoms to watch for.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Amantadine can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
Amantadine should not be given to a child younger than 1 year old.
What Are The Side Effects Of Amantadine
Amantadine is a drug that helps treat Parkinsons disease and other conditions. People can experience mild to severe side effects while taking this medication.
Amantadine comes in capsule, tablet, or liquid forms. The brand names for amantadine are Gocovri and Osmolex ER.
The most common side effects are nausea, dizziness, and sleeping problems. Some less common but more severe side effects include changes to the central nervous system and the heart, as well as suicidal thoughts or actions.
This article looks into the uses for amantadine and the side effects that a person might experience.
Amantadine can treat a few conditions, and doctors most often prescribe it to treat Parkinsons disease.
Amantadine can also help with movement-related side effects of antipsychotic medications. The medical name for these effects is extrapyramidal symptoms .
Extrapyramidal symptoms are similar to the movements that characterize Parkinsons disease. They may involve muscle spasms, jerkiness, tremors, and slowness.
Amantadine can also prevent and treat the influenza A virus by helping to stop the virus from replicating. It is not, however, a substitute for an annual flu vaccination.
The most common side effects of amantadine, affecting 510% of people who take the recommended dosage, include:
Infrequent side effects, affecting 0.1 to 1% of people, include:
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Suicidal Thoughts Or Actions
Suicidal thoughts or actions are a rare side effect of amantadine, occurring in fewer than 0.1% of people.
Many people affected in this way have taken amantadine for influenza prevention or treatment. This side effect can develop in people with no history of psychiatric illness.
People taking amantadine, and those close to them, should look carefully for any behavioral changes, including agitation, personality changes, paranoia, depression, and anxiety.
Proper Use Of This Medicine Take This Medicine Only As Directed By Your Doctor
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For People With Parkinson’s Disease
- Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. During the first few weeks of treatment in particular, your dose may require adjusting.
- Stay as active as possible and exercise regularly as much as you are able. You may walk more slowly than before but a daily walk is good exercise and may help to loosen up stiff muscles.
- If you are a driver you should tell the DVLA and your insurance company that you have Parkinson’s disease. Depending on the severity of symptoms and the medicines that you are taking, you may still be allowed to drive following a medical assessment.
- Treatment with medicines for Parkinson’s disease can sometimes cause problems with impulsive types of behaviour. If you notice any changes in your behaviour, such as an increased desire to gamble, binge eat, or spend excessively, or an increased sex drive, you must let your doctor know as soon as possible.
- Continue to take amantadine regularly. Stopping treatment suddenly can cause serious problems. Your doctor will probably want you to reduce your dose gradually if this becomes necessary.