What Causes Parkinsons Disease
The deterioration or impairment of the nerve cells in the area of the brain is called as substantia nigra that causes Parkinsons disease. When these neurons functions normally they produce dopamine which is an essential brain chemical. Dopamine allows communication between corpus striatum and substantia nigra. The muscle movement is coordinated properly with this communication. When there is no dopamine then there is abnormal nerve functioning and causes inability to control body movements.
Primary Symptoms of Parkinsons Disease
Tremors: These tremors usually appear in the fingers, chin, hands, mouth, forearms and foot.
Poor Balance: The reason for poor balance is the loss of reflexes that maintain posture. It typically results in unsteady balance that leads to fall.
Slow movement : It slows down the voluntary movement that includes walking, sitting up and standing up. This is due to delay in transmission signals through the brain to the muscles. It can cause difficulty in initiating walking and in serious cases can result in freezing episodes once walking has started.
Rigidity: Stiff muscles or rigidity generates muscle pain which increases during movement.
Secondary Symptoms of Parkinsons Disease
- Excessive salivation
- Drooling or coughing and choking
- Loss of intellectual capacity
- Dry skin and scaling on the face or scalp
- Whispery and soft voice
- Loss of bladder control or bowel
What Is Parkinsons Disease
Parkinsons disease often known as Kampavata in Ayurveda is a neurological disorder that affects 1% of the population over age 65 years. With the help of ayurvedic treatment for Parkinsons in India, you can combat this disease. Parkinsons is a long-term degenerative disorder of the central nervous system which mainly affects the motor system of the body. This lethal disease deteriorates the nerve junctions which are situated at the base of the brain. This disease gradually affects muscle control and movements of the body. Patients who are suffering from this disease often lose control over their body movement and experience tremors or shivering in hand or limb in resting state.
Getting Around In India
Indira Gandhi International Airport is the busiest airport in the country and is located in Delhi. The airport serves domestic and international flights. It connects the city with almost every country around the world and serves budget airlines such as Air Asia India, Go Air, and IndiGo. There are three other main international airports in Mumbai, Chennai, and Bengaluru.
The most affordable way to travel around the city is by bus although it can be very crowded. Buses are very reliable and fast. Airport taxis are available as a quick, easy, and hassle-free transportation mode especially for tourists who carry big baggage.
The best way to get around India is by train. Trains are everywhere and quite affordable with many different classes. The most popular class for travel is the Sleeper Class. It is best to purchase train tickets online.
Buses are a nice option for short-distance travel. Some of the buses can be very uncomfortable but there are luxury buses with air conditioning. Tourists can purchase tickets online, in the station, or even on the buses.
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Parkinsons Disease Stem Cell Treatment
Parkinsons disease happens when there is a problem with certain nerve cells in the brain. This disease affects the way you move because of the inadequate production of dopamine, which is an important chemical that sends signals to the part of the brain that controls movement. Parkinsons is a progressive disease whose symptoms take a few years to surface.
Parkinsons is an illness that affects the central nervous system with a direct blow on the brain and spinal cord and usually only affects adults. More specifically, this disease damages a group of nerve cells in the deepest part of the brain called the Basal Ganglia. There are quite a few reasons leading to Parkinsons disease, including aging and poisons in the environment. To cure Parkinsons disease, stem cell treatment is highly popular.
These nerve cells make and use a brain chemical called dopamine to send messages to other parts of the brain to coordinate body movements. When someone suffers from Parkinsons disease, the dopamine levels are low. So, the body doesnt get the right messages required to move normally.
About 1 million people in the United States alone have Parkinsons, and both men and women can be affected by it. It usually affects the elderly population, someone older than 50, and it becomes common as people get older.
- Problems with balance or walking
Tremor, which essentially means shaking or trembling. Tremors may affect your hands, arms, or legs.
Treatment And Surgery For Parkinsons Disease In India :
India is widely known in the world for its world-class medical and health care services. This has made India worlds number one medical tourism destination People are attracted towards the best quality of healthcare services, accredited medical facilities, and internationally trained and qualified health care professionals and travel to India for their health care needs. The services encompass everything from primary health check ups to major surgical procedures. The hospitals of India offers complete treatment of Parkinsons disease. India has the most sophisticated hospitals of the world which have hi-tech equipments, state-of-the-art comforts and facilities, skilled doctors and compassionate, dedicated nurses. Complimentary therapies like, Acupuncture, Alexander technique, Aromatherapy, Herbal medicine, Naturopathy, Reiki, Yoga, Reflexology, massage therapy, etc. are provided by proffessionals who are extremely proficient in their field.
Cities in India that offers Treatment and Surgery for Parkinsons Disease
| Mumbai |
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Incision On Skin And Skull
After the imaging scans, the patient will be taken to the operating room. The stereotactic head frame remains secured and it prevents any movement of the head while placing the electrodes. The patient may remain awake during this part of the surgery. The doctor may give a mild sedative to make it more comfortable during the skin incision. Later, the sedation is stopped so that the doctors can talk to the patient and perform the tasks.
The hair is shaved and an incision is made on the skin on the top of the head to expose the skull. The surgeon will then make two burr holes using a drill on the left and right sides of the skull. Through these holes, electrodes are passed into the brain.
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Complementary Therapies For Parkinsons Disease :
Massage therapy, Yoga, Tai Chi, Hypnosis, Acupuncture, etc. can give mild benefits. Benefits of Parkinsons Disease Treatment Medications can help manage problems with walking, movement and tremor by increasing the brains supply of dopamine.Deep brain stimulation safely and effectively manages some of the most disabling motor symptoms of Parkinsons disease and essential tremor. The procedure enables people with some movement disorders and related symptoms to have greater control over their movements, allowing them to have more freedom to live and work.Physical therapy may be advisable and can help improve your mobility, range of motion and muscle tone.
A speech therapist or speech pathologist can improve problems with speaking and swallowing. Although speech therapy involves a large time commitment , the benefits will be impressive. In the long run, it will potentially improve all your social interactions to boot.
While conventional treatments generally focus on symptoms, a range of other practices and therapies focus on overall well-being or different components of it and have benefited a lot of patients. Examples include regular exercise, complementary therapies and nutrition supplements.
Diagnosis For Parkinsons Disease :
Most individuals with Parkinsons disease are diagnosed when they are 60 years old or older, but early-onset Parkinsons disease also occurs.
- Difficult to diagnose, early symptoms may be dismissed as normal effects of aging.
- The Hoehn and Yahr scale and the Unified Parkinsons Disease Rating Scale are used for diagnosis.
- Tests are used to measure mental capacity, behavior, mood, daily living activities, and motor function. No blood or laboratory tests.
- Brain scans and laboratory tests are used to rule out other diseases.
- Diagnosis is based on the medical history and a neurological examination
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Treatment For Parkinsons Disease
Parkinsons disease can be treated with the help of some specific medications. Deep Brain Stimulation is one of the most common surgical procedures for those patients who are suffering from Parkinsons disease. This surgery helps in slowing the movements and reduces the severity of muscle rigidity. During the surgical procedure, a wire inside the brain is connected with a pacemaker type device which is implanted under the skin in the chest.
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Symptoms Begin Gradually Often On One Side Of The Body Later They Affect Both Sides They Include
- Symptoms begin gradually, often on one side of the body. Later they affect both sides. They include
- Trembling of hands, arms, legs, jaw and face
- Stiffness of the arms, legs and trunk
- Slowness of movement
- Poor balance and coordination
As symptoms get worse, people with the disease may have trouble walking, talking, or doing simple tasks. They may also have problems such as depression, sleep problems, or trouble chewing, swallowing, or speaking.
There is no lab test for PD, so it can be difficult to diagnose. Doctors use a medical history and a neurological examination to diagnose it.
PD usually begins around age 60, but it can start earlier. It is more common in men than in women. There is no cure for PD. A variety of medicines sometimes help symptoms dramatically. Surgery and deep brain stimulation can help severe cases. With DBS, electrodes are surgically implanted in the brain. They send electrical pulses to stimulate the parts of the brain that control movement.
Parkinsons disease symptoms and signs may vary from person to person. Early signs may be mild and may go unnoticed. Symptoms often begin on one side of your body and usually remain worse on that side, even after symptoms begin to affect both sides.
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Electrophysiology And Transcranial Magnetic Stimulation
Visual evoked potentials in PD patients have been known to be abnormal with prolonged P100 seen in two-thirds of the patients observed. Muthane et al., studied abnormalities in evoked potentials in EOPD patients. Evoked potentials, both visual and auditory, were assessed in EOPD and found to be abnormal in 26% each. There was higher incidence of brainstem auditory evoked potential abnormalities in EOPD compared to classical PD.
Transmagnetic stimulation is an important tool used to assess the central motor circuitry and has been used extensively to study the pathophysiology of PD. In India, there have been a few studies of TMS on PD patients at SCTIMST and AIIMS. Bhatia et al., studied about threshold intensity in PD patients. Studies from SCTIMST elaborated about long-term potentiation and depression in PD, its effect after acute dopamine therapy, and also the effect of cerebellar inhibition on motor plasticity in patients with LD-induced dyskinesias .
New Drug To Treat Parkinsons Disease To Be Introduced In India
Apomorphine, which is derived from the water lily plant, has been found to control several neurodegenerative symptoms of Parkinson’s and aid in improvement of the condition in many cases.
The blue water lily was used by ancient Egyptians as a sedative and intoxicant. Centuries later, scientists have now discovered that a derivative of the plant has a significant role to play in the treatment of Parkinsons disease. Apomorphine, which comes from the plant, has been found to control several neurodegenerative symptoms of Parkinson’s and aids in improvement of the condition in many cases. This drug is now set to be available for the first time in India to treat those suffering from Parkinsons disease.
Around 300 to 400 people for every 100,000 population are diagnosed with Parkinsons in India, states Dr Shivam Om Mittal, Parkinsons Specialist from Bengaluru. It is expected to more than double by the year 2030 and will be a major non-communicable degenerative disorder among the people in the country. Speaking to the media on Thursday at an event held at Vikram Hospital in the city, introducing the drug to the Indian market, he along with several other experts talked about the impact of introducing the drug in India.
What is Parkinsons disease?
Direct Brain Stimulation
It is not as though the drug is not without its drawbacks.
Apomorphine pens
Apomorphine delivering pump
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Stem Cell Treatment For Parkinsons Disease
The latest research has revealed that Umbilical Cord Mesenchymal Stem Cells can differentiate into nerve cells and neovascularise immunomodulate when injected into the affected area, thereby improving symptoms and prolonging lives. Steroids and other disease-modifying drugs cannot cover all the symptoms and are aimed at managing only specific symptoms. Again, the concern of critical side effects of drugs is also there. With MSC treatment, there is no such concern.
In Viezec, we use the unique technology of Mesenchymal stem cells extracted from Whartons jelly for treating MS. WJ-MSCs offer a cost-effective and pain-free collection method that may be cryogenic ally stored and is extremely favorable for tissue engineering purposes. They might help in three prominent ways prevent damage, repair damage, and develop new medicines. The treatment will take place in multiple steps comprising the following.
Parkinsons disease stem cell Treatment Aftercare: The patients will be asked to visit the doctors for evaluation. You will be provided counseling for a speedy recovery.
Symptoms Of Parkinson’s Disease
At the early stages, the symptoms of Parkinson’s disease are similar to manifestations of other neurological disorders, which complicates the diagnostics process. However, the disease has three main symptoms:
- Restraint movements and muscles : its difficult to a person to perform regular movements
- Inflexible muscles : muscle tone is increased in flexion and extension of extremities
- Extremities trembling : most often occurs in fingers, but may be in other parts of the body.
The other signs of Parkinson’s disease can be:
- Changed handwriting
- Unreasonable anxiety or fear.
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Fortis Memorial Research Institute Gurgaon
How Much Does Parkinsons Disease Treatment Cost In India
The cost of Parkinsons disease treatment in India varies from 7000-9900 USD considering the number of travelers, type of treatment opted, total stay in India and more.
How much does deep brain stimulation cost in India?
The cost of deep brain stimulation surgery in India is around 15,000-27,000 USD.
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Parkinsonism Treatment Hospital In Mumbai India
Movement disorders is an umbrella term for a group of neurological conditions that trigger abnormally increased voluntary and involuntary movement as well as reduce the pace of the former. These can be a result of many factors like genetics, infections, a side-effect of certain medications, damage or injury to the brain and spinal cords, metabolic disorders and cardiovascular diseases like stroke. While some movement disorders can be easily treated by medicinal, therapeutic and surgical means, others need to be managed lifelong so as to improve the quality of the patients life.
Definition Of Parkinsons Disease:
Parkinsons is a chronic progressive degenerative disorder affecting mainly people above the age of 60. Males are more prone than females. Worldwide prevalence is 0.3 1 %. If we talk about India alone, Parkinsons disease is the second leading chronic degenerative disorder after Alzheimer’s, with a prevalence that is directly proportional to age. Between the age of 70-79 years, it could be as high as 280 for a Hundred thousand people.
Parkinsons disease is a disorder that impacts the brain and leads to difficulty with balancing, coordination and walking. Along with this, the patient also experiences shaking and stiffness.
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