Why India For Parkinsons Disease Treatment
India has several JCI accredited hospitals that are well-known for their state-of-the-art infrastructure, highly skilled medical professionals and well-trained nursing staff. These medical services provide affordable healthcare services to patients across the globe.
Medsurge India is a reputed and trusted health assistance partner that provides services in all major cities in the country. They have tie-ups with multiple super-specialty and multi-specialty hospitals across the country. MedSurge team makes sure that the patients get the best of healthcare.
Stem Cell Therapy For Parkinsons Disease
Parkinsons disease is a progressive disorder of the nervous system affecting movements. It develops gradually, starting with the barely noticeable tremors but in the later stages, it is associated with frequent body stiffness and slowing-down or complete loss of movement. People with Parkinsons disease may experience muscular tremors, stiff muscles, delayed muscular movements and issues with locomotor actions such as balance, walking, etc. With recent technological advancements in stem cells, it is possible to proactively alter the effects of the disease and live a full, happy, healthy life. Having the potential to significantly impact the development of diseased state, stem cell treatment for Parkinsons can create dopamine-producing cells which enhance normal communication between neurons and provide a vastly improved quality of life.
Weather And Climate In Delhi
Delhi has a high variation of temperature between summer and winter. Summer in Delhi can get really hot with an average temperature of around 32°C. The season starts in April to June and the temperature can reach as high as 46°C. It is advisable to avoid this season if youre planning to do a lot of outdoor activities. The monsoon starts in late June to mid-September. The temperature usually falls to an average of 29°C, but its rainy and humid.
The temperature plummets during winter, ranging between 6°C to 7°C. This season starts in November and lasts until March. October to March is the best time to visit Delhi because the weather is neither too hot or too cold.
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Contracted Influenza Infection New Study Says You Have 70% Higher Risk Of Parkinsons 10 Years Later
For decades, neurologists have suspected there may be a link between the flu and Parkinsons disease, a chronic and progressive disorder of the nervous system marked by problems with movement, cognitive changes and a range of other symptoms.
Will a flu vaccination reduce the risk?
Weather And Climate In India
There are four climatological seasons in India.
- Summer or pre-monsoon season starts in March and ends in May. April or May is the hottest month. The average temperature is around 23 to 42 °C.
- Monsoon or rainy season lasts for three months from June to September. The season is usually humid and rainy. South India usually receives more rainfall.
- The post-monsoon or autumn season starts from October to November. The sky is usually cloudless.
- Winter occurs from December to February. December and January are the coldest months in the country with an average temperature of 10 to 15 °C and climb steadily from February. This is the peak season for tourism.
The best time to visit India is in the month of March or October when the weather is warm and sunny.
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Stem Cells Therapy For Parkinsons Treatment: Advancells Protocol
Advancells is excited by the prodigious prospects of stem cells in treating various diseases, hence we are constantly updating our knowledge and technology to suit unique specifications of each patient. At Advancells we are exploiting the most potent stem cells isolated from patients own Bone Marrow or Adipose tissue or maybe both depending upon the assessment. Our top priority is to provide a very comprehensive, individualized stem cell therapy for Parkinson, which is best suited for the patients undergoing treatment.With extensive research these challenges are now comprehensible to therapeutic ventures resulting in new treatments of Parkinsons Disease using autologous treatment or allogenic transplant for adipose-derived mesenchymal stromal cells treatment and bone marrow stromal cells treatment. This new insight on the treatment of Parkinsons Disease has helped in identifying the potential to overcome Parkinsons Disease with stem cells, primarily using autologous stem cell transplant in form of hematopoietic stem cell transplant or mesenchymal stromal cells treatment.
Procedure of Treatment of Parkinsons through Stem Cells Therapy
Parkinsons Disease: Diagnosis And Tests
No specific test exists to diagnose Parkinsons disease. A neurologist who specializes in diagnosing neurological disorders diagnoses Parkinsons disease based on your signs & symptoms, a thorough neurological & physical examination, and medical history.
The doctor may also recommend blood tests to check whats the main reason for the cause of symptoms.
Apart from this, your doctor may recommend a specific single-photon emission computerized tomography scan called a dopamine transporter scan and other imaging tests such as MRI, ultrasound, and PET scans. Although, these tests arent much help in diagnosing Parkinsons disease.
Your doctor may suggest regular follow-up appointments to evaluate the symptoms over time to diagnose Parkinsons disease.
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Parkinson’s Disease: Diagnostics In India
The main task of a neurologist during the examination of a patient is to determine whether Parkinsonism is primary or secondary disease.
The primary Parkinson’s disease is a violation of dopamine production.The symptoms of the secondary Parkinson’s disease are similar to the primary, but are caused by other disorders. Accurate diagnostics at the early stages differentiates one pathology from another and helps to choose the optimal method of treatment.
Complex diagnostics of Parkinson’s disease in Indian clinics includes:
- Complete blood counts for patients general condition evaluation
- Electroencephalography for evaluating brain electrical activity
- Electromyography analyzes the state of muscles and displays the rhythm of the extremities tremor
- CT to determine the amount of produced dopamine.
What Is The Diet For Parkinson’s
Parkinson’s patients should remember that they ought to control their diet in order to manage the disease better. Being healthy and being the right weight can help them cope with the disease and reduce the symptoms.
- It is extremely vital for people with Parkinson’s to ensure their diet contains a lot of fiber. Some of the foods with high fiber include peas and beans, whole grain bread, vegetables, cereals, rice, and fresh fruits.
- Food that has a lot of cholesterol or saturated fat is definitely a big No No.
- Reduce the amount of milk and curds a person consumes, and sugar and salt intake should also be restricted.
- People with Parkinson’s should consume a lot of water – at least 8 glasses per day.
- Avoid alcohol, as it might interfere with the medications.
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Common Drugs For Parkinson’s Disease
Levodopa and carbidopa . Levodopa is the most commonly prescribed medicine for Parkinsonâs. Itâs also the best at controlling the symptoms of the condition, particularly slow movements and stiff, rigid body parts.
Levodopa works when your brain cells change it into dopamine. Thatâs a chemical the brain uses to send signals that help you move your body. People with Parkinsonâs donât have enough dopamine in their brains to control their movements.
Sinemet is a mix of levodopa and another drug called carbidopa. Carbidopa makes the levodopa work better, so you can take less of it. That prevents many common side effects of levodopa, such as nausea, vomiting, and irregular heart rhythms.
Sinemet has the fewest short-term side effects, compared with other Parkinsonâs medications. But it does raise your odds for some long-term problems, such as involuntary movements. An inhalable powder form of levodopa and the tablet istradefylline have been approved for those experiencing OFF periods, OFF periods can happen when Parkinsonâs symptoms return during periods between scheduled doses of levodopa/carbidopa.
People who take levodopa for 3-5 years may eventually have restlessness, confusion, or unusual movements within a few hours of taking the medicine. Changes in the amount or timing of your dose will usually prevent these side effects.
Dopamine agonists. These drugs act like dopamine in the brain. They include pramipexole , rotigotine , and ropinirole , .
The Typical Symptoms Of Parkinson’s Disease Are:
- Slowed movement : Almost all the movements can only be performed slowly. People who are affected walk very slowly and hesitantly and can only take short steps. They find it hard to start moving, and taking the first step is particularly difficult. But, once they start moving, it is difficult for them to stop. With the progress of the disease, they stop swinging their arms when walking. Due to reduced activity in the facial muscles, the face becomes mask-like. Speech becomes quiet and swallowing also becomes harder. The early symptoms of Parkinson’s are subtle and occur gradually, but in some people the disease progresses more quickly than in others. As the disease progresses, the shaking, or tremor, which affects the majority of people, begins to interfere with daily activities.
- Muscle stiffness: The muscles of the arms, legs, and neck can become stiff and tense. The muscles stiffen up and cannot be moved at all or with great difficulty. This excessive tensing of the muscles often causes aches and pains in the body.
- Tremors: Most people with Parkinson’s suffer from tremors. These tremors decrease or hampers movement, and these tremors can be particularly seen in the hands.
- Other symptoms: Difficulty in swallowing, chewing, speaking, urinary problems, constipation, skin problems, and sleep disruptions.
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The Investigation In Mice
In their recent study paper, the scientists refer to research suggesting that neurotrophic factors molecules that help neurons survive and thrive could, in theory, restore the function of neurons that produce dopamine. However, the clinical benefit of these factors had yet to be proven.
The team focused on bone morphogenetic proteins 5 and 7 . They had previously shown that BMP5/7 has an important role in dopamine-producing neurons in mice.
In the latest study, the scientists wanted to see whether BMP5/7 could protect the neurons of mice against the damaging effects of misfolded alpha-synuclein proteins.
To do this, they injected one group of mice with a viral vector that caused misfolded alpha-synuclein proteins to form in their brains. They used other mice as a control group. The scientists then injected the mice with the BMP5/7 protein.
What Are The Side
Some of the patients who were treated with Kappikacchu have shown mild side effects, which include headache, dystonia , fatigue, tremors, syncope and thirst. Other drugs, such as Amantadine, which improves symptoms in about 50% of the patients may cause edema, confusion, and liver reticularis. Side effects of other drugs include confusion, delirium and psychosis.
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What Is Parkinson’s Disease
Parkinson’s disease belongs to a group of conditions called motor system disorders, which are the result of the loss of dopamine-producing brain cells. Parkinson’s is a disease of the nervous system that mostly affects older people, which typically begins at the age of 50. It is a progressive disease that, in most cases, will continue to gradually get worse.
One of the worst things about the disease is that it can be very hard to cope with the disease and live with it, because it severely restricts mobility and as a result makes daily activities increasingly difficult. Many people who develop Parkinson’s will require nursing care. As the cause of Parkinson’s is not known, there is no cure for the disease, but there are effective treatments that can relieve the symptoms.
How Can Stem Cell Technology Help
Stem cell technologies show promise for treating Parkinson’s Disease and may play an increasing role in alleviating at least the motor symptoms, if not others, in the decades to come.
“We are in desperate need of a better way of helping people with Parkinson’s disease. It is on the increase worldwide. There is still no cure, and medications only go part way to fully treat incoordination and movement problems,” said Claire Henchcliffe, from Weill Cornell Medical College in the US.
“If successful, using stem cells as a source of transplantable dopamine-producing nerve cells could revolutionize care of the Parkinson’s disease patient in the future,” said Malin Parmar, from Lund University in Sweden.
“A single surgery could potentially provide a transplant that would last throughout a patient’s lifespan, reducing or altogether avoiding the need for dopamine-based medications,” said Parmar.
In the past, most transplantation studies in PD used human cells from aborted embryos. While these transplants could survive and function for many years, there were scientific and ethical issues — foetal cells are in limited supply, and they are highly variable and hard to quality control.
Some patients were treated, while another developed allergy with the graft.
This approach is now rapidly moving into initial testing in clinical trials, researchers said.
The first systematic clinical transplantation trials using pluripotent stem cells as donor tissue were initiated in Japan in 2018.
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New Parkinson’s Treatment Launches In India
06 December 2018 | News
Apomorphine, available both as injections and infusion pumps, is manufactured by Britannia Pharmaceuticals of the UK.
In a boon to patients in the middle stages of Parkinsons Disease, Vikram Hospital Bengaluru, in association with the UK-based specialty pharmaceutical company Britannia Pharmaceuticals, has launched Apomorphine for the first time in India. This powerful new drug stimulates the production of dopamine by nerve cells in the brain, providing quick and effective relief to patients and improving their quality of life. Apomorphine, available both as injections and infusion pumps, has been popular in the West for over 15 years in the management of Parkinsons, but Indian patients could not benefit from it until now.
Said Dr Shivam Om Mittal, Parkinsons Disease & Movement Disorders Specialist, Vikram Hospitals, Bengaluru: The current prevalence of Parkinsons Disease in India is around 300-400 out of 100,000, which is expected to more than double by 2030. It will be a major non-communicable degenerative disorder along with dementia to burden the healthcare system of India. Though majority of the patients are above 50 years of age, no age group is immune to Parkinsons Disease. Of late, its incidence in younger population is also on the rise.
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Why The International Patients Trust Us
- We Provide the best Hospitality Experience in India which are As Per International Standards and the team of Stem Cell Experts with an international professional standard Ensures Best Stem Cell Treatment to the patients.
- We are Provider Of Healthy life And Improve the Standards Of living For the International patients By Providing affordable low-cost Stem Cell treatment, best treatment facility with International Standards and a homely atmosphere.
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What Ayurveda Says About Parkinsons Disease
Parkinsonism is a condition where movement is affected and hence is a Vaatha roga called as Kampa Vaatha. Kampaimplies the tremor associated with the condition. Both internal medications and external therapies are essential to break the pathology of the condition. Suitable Panchakarma therapies, which are the five cleansing therapies of Ayurveda, will be very effective to eliminate the accumulated toxins in body. The protocol of treatment involves internal medications to enhance digestion, clear the channels of circulation, break down aama and regulate function of vaatha dosha are given. The wide range of formulations includes decoctions, powders, medicated ghee, confections, pills, etc. Internal administration of ghee medicated with brain tonics is specifically important here. The procedure is called as Snehapaana. Along with them the following external therapies are performed:
- Udvarthana: A procedure where medicinal powder is rubbed all over body in a systematic manner for a fixed duration.
- Kizhi: Application of medicine filled poultice over body after heating it, in a synchronized manner. This is particularly effective for nerve stimulation.
- Dhaara: Pouring of warm medicated liquid or oil all over body in a specific pattern for a fixed duration.
- Abhyanga and Ooshma sweda: Oiling the body and steaming is a very effective method to normalize abnormal Vaatha dosha
Types Of Parkinsons Disease
- Primary Parkinsons
- Once the hospital chosen, we will request you for the passport details of the travellers
- The next step is to get the visa invite from the selected hospital.06
- 07You may then apply for the visa to India for the patient, using this invitation at the Indian consulate, embassy/high commission in your country.
- Alongside, we will send the bank details either of our company or of the Selected hospital, whichever you prefer- so that you may transfer the funds as quoted.08
- 09After fund transfer, all the travel and treatment related arrangements will start to offer you a hassle -free experience as explained above.
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Revolutionary Treatment For Parkinson’s Enters India
06 December 2018 | News
Nanavati Super Speciality Hospital in collaboration with Parkinsons Centre of Excellence, Kings College, London launch the revolutionary new modality for the treatment of Parkinsons for the first time in India.
Nanavati Super Speciality Hospital in association with Kings College, London launched a revolutionary treatment that will change the way Parkinsons has been treated in India. Apomorphine Pen & Pump, the treatment that will radically change the life of a Parkinsons patient will now be available in India. The treatment was launched in Mumbai recently by the Health Minister of Maharashtra, Dr. Deepak Sawant and Paresh Rawal, Actor and Member of Parliament.
Parkinsons disease is one of the common neurodegenerative diseases affecting the people over the age of 55 years. Parkinsons is characterized by slowness, stiffness and tremors are a special neurodegenerative disorder with very few therapeutic options available. In India, the prevalence of this disease advances between the age of 70-79. It is caused by dopamine deficiency which is a chemical neuro transmitter in the brain mainly in the centers controlling the mobility.
Apomorphine is a highly selective Dopamine receptor stimulator, which promotes the release of dopamine in the brain from the nerve cells that is otherwise absent.