Sunday, August 14, 2022

Is Parkinsonism The Same As Parkinson’s Disease

What Is The Outlook For Persons With Parkinsons Disease

Ask the MD: Is parkinsonism the same as Parkinson’s disease?

Although there is no cure or absolute evidence of ways to prevent Parkinsons disease, scientists are working hard to learn more about the disease and find innovative ways to better manage it, prevent it from progressing and ultimately curing it.

Currently, you and your healthcare teams efforts are focused on medical management of your symptoms along with general health and lifestyle improvement recommendations . By identifying individual symptoms and adjusting the course of action based on changes in symptoms, most people with Parkinsons disease can live fulfilling lives.

The future is hopeful. Some of the research underway includes:

  • Using stem cells to produce new neurons, which would produce dopamine.
  • Producing a dopamine-producing enzyme that is delivered to a gene in the brain that controls movement.
  • Using a naturally occurring human protein glial cell-line derived neurotrophic factor, GDNF to protect dopamine-releasing nerve cells.

Many other investigations are underway too. Much has been learned, much progress has been made and additional discoveries are likely to come.

Important Points About The New Medications

With multiple new medications available for the treatment of PD, there is more hope than ever that Parkinsons symptoms can be successfully managed for many years. A few things to consider:

  • For people whose symptoms are difficult to control, these new treatments are welcome additions to what was previously available and many people with PD have been using these new medications with significant benefit.
  • On the other hand, many of the newly-approved medications have the same mechanisms of action as older medications so they are not breaking new ground in treating symptoms.
  • In addition, for some people, the effect on symptoms may be mild or not substantial.

These caveats may mean that your physician has not suggested a medication change for you. It is also important to note that despite all the new medications, carbidopa/levodopa remains the most potent medication to treat the motor symptoms of PD.

If your doctor does choose to try one of the new options, there may be multiple paths that your doctor can take when contemplating a medication adjustment. Often trial and error is the only way to determine the best medication regimen for you, so you may need to practice some patience as you work together with your doctor to determine what works or doesnt work.

Ayurvedic Treatment For Parkinsons Disease

Handshake is good but shaking hands are horrible. Holding a cup and sipping it becomes a challenge for the patient with Parkinsons disease. There are no treatments for this with a conventional system of medicines. Western sciences had already accepted their defeat well in advance. Because of this PD rules the medical world nowadays. But there is another side to the story too. Parkinsons disease is a condition which we can treat well in Ayurveda . Most importantly, in Ayurvedic treatment for Parkinsons disease is possible. Early you join some Ayurvedic hospitals better results you get. Chronicity adds complexity to every disease and especially in neurodegenerative diseases.

Generally, in name of Ayurveda treatment of Parkinsons disease, patients just keep on looking for herbal nerve tonics. But the complex degenerative disorder needs more care than herbal nerve tonics.

It is important to understand the disease for the proper treatment of Parkinsons disease.

Here are the details of the disease and all aspects of Ayurvedic Treatment for Parkinsons Disease.

Contents

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Regular Physical Activity May Help Slow Parkinson’s Disease

A few hours of exercise a week may help slow Parkinson‘s disease, even if it’s just moderate activity such as walking or gardening, a new study suggests.

The key is to be consistent, the researchers found.

“Although medications can provide people with Parkinson’s some symptom relief, they haven’t been shown to slow the progression of the disease,” said study author Dr. Kazuto Tsukita, of Kyoto University in Japan.

“We found that regular physical activity, including household tasks and moderate exercise, may actually improve the course of the disease over the long run,” he said. “Best of all, exercise is low-cost and has few side effects.”

Tsukita and his team assessed physical activity in 237 people with early-stage Parkinson’s. The participants were followed for up to six years.

While their activity levels at the outset did not affect the progression of their Parkinson’s, those who regularly got at least four hours a week of moderate to vigorous exercise during follow-up had slower declines in balance and walking ability than those who were less active.

The patients’ Parkinson’s symptoms were rated on a scale of 0 to 4, with higher scores indicating more severe symptoms, according to findings published online Wednesday in Neurology.

More information

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What Causes Parkinsons Disease

Possible Skin Test for Detecting Parkinson

Parkinsons disease occurs when nerve cells in an area of the brain called the substantia nigra become impaired or die. These cells normally produce dopamine, a chemical that helps the cells of the brain communicate . When these nerve cells become impaired or die, they produce less dopamine. Dopamine is especially important for the operation of another area of the brain called the basal ganglia. This area of the brain is responsible for organizing the brains commands for body movement. The loss of dopamine causes the movement symptoms seen in people with Parkinsons disease.

People with Parkinsons disease also lose another neurotransmitter called norepinephrine. This chemical is needed for proper functioning of the sympathetic nervous system. This system controls some of the bodys autonomic functions such as digestion, heart rate, blood pressure and breathing. Loss of norepinephrine causes some of the non-movement-related symptoms of Parkinsons disease.

Scientists arent sure what causes the neurons that produce these neurotransmitter chemicals to die.

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Characteristic Clinical Features Of Pd

PD can be diagnosed with considerable accuracy, particularly by neurologists specializing in diagnosis and management of movement disorders , when robust clinical criteria are used such as those of the Queen Square Parkinson Disease Brain Bank, which have inclusion criteria and exclusion criteria as well as presence of supportive features . Asymmetry is an important supportive feature in that the other major degenerative parkinsonian disorders MSA and PSP are usually symmetrical. Response to dopamine replacement therapy is typical of PD, whereas MSA and PSP have limited response to such therapy. The exclusion criteria also include absence of family history of movement disorder, but this is criterion is often ignored today given increasing evidence of genetic determinants of PD .

Treatment For Atypical Parkinsonism Symptoms

Because PD medication response is poor in these syndromes, treatment focuses on symptom management e.g. physical therapy for fall prevention, speech therapy to maximize communication, swallow therapy to prevent aspiration.

Other symptoms that can be addressed include dystonia, myoclonus, blood pressure dysfunction and urinary dysfunction.

Tips and takeaways:

  • Atypical parkinsonism is a very complicated group of diseases that are hard to diagnose. Sometimes a neurologist will change the diagnosis as new symptoms develop or become more apparent.
  • Despite the fact that these conditions typically do not respond well to medications for PD, many of the presenting symptoms can be addressed, so make sure to raise all of your concerns with your neurologist.

Do you have a question or issue that you would like Dr. Gilbert to explore? Suggest a Topic

Dr. Rebecca Gilbert

APDA Vice President and Chief Scientific Officer

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The Light Treatments Available Now

Those already suffering with Parkinsons dont need to wait for the trial results, as there are light therapy products from SYMBYX already available on the market.

It is legal and regulated and its available for purchase, Dr Wayne Markman, CEO of SYMBYX an Australian medical technology company told 7NEWS.

What Are The Symptoms Of Atypical Parkinsonian Disorders

Ask the MD Is parkinsonism the same as Parkinson’s disease

Like classic Parkinsons disease, atypical Parkinsonian disorders cause muscle stiffness, tremor, and problems with walking/balance and fine motor coordination.

Patients with atypical Parkinsonism often have some degree of difficulty speaking or swallowing, and drooling can be a problem. Psychiatric disturbances such as agitation, anxiety or depression may also be part of the clinical picture.

Dementia with Lewy bodies can cause changes in attention or alertness over hours or days, often with long periods of sleep during the day. Visual hallucinations typically of small animals or children, or moving shadows in the periphery of the visual field are common in DLB. DLB is second only to Alzheimers disease as a cause of dementia in the elderly, and it most commonly affects patients in their 60s.

Patients with progressive supranuclear palsy may have difficulties with eye movements, particularly when looking downward, and with balance when descending stairs, for instance. Backward falls are common and may occur during the early course of the disease. PSP is not usually associated with tremor, unlike Parkinsons disease.

Parkinson’s Disease and Movement Disorders Center

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Ayurveda About Parkinsons Disease

In Ayurvedic literature, the exact detailing of any disease is not as such available. There are certain conditions, when we explore these conditions, we can find the treatment of many conditions. Therefore in parkinsonism, the main thing is to find out the exact pathophysiology in terms of Doshas. This helps in reaching proper Ayurveda treatment and a solution to the problem.

Before we proceed to the Ayurvedic treatment for Parkinsons disease. Here, we need to know about certain facts about PD according to Ayurveda.

  • Vata is main dosha in this disease.
  • Vata is not able to express itself properly.
  • If we look at gunas, then we can see a clear relation between the movement and stability .
  • Therefore we need to co-relate everything with doshas and gunas.
  • The Ayurveda treatment for Parkinsons approach is primarily based on pathophysiology of the disease.
  • Reversal of pathology helps in the complete reversal of the disease.

We at Sukhayu work on these principles only. We dont work on lame analogies of the diseases.

Incidence Of Parkinsons Disease

Its estimated that approximately four people per 1,000 in Australia have Parkinsons disease, with the incidence increasing to one in 100 over the age of 60. In Australia, there are approximately 80,000 people living with Parkinsons disease, with one in five of these people being diagnosed before the age of 50. In Victoria, more than 2,225 people are newly diagnosed with Parkinsons every year.

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What Are Atypical Parkinsonian Disorders

Atypical Parkinsonian disorders are progressive diseases that present with some of the signs and symptoms of Parkinsons disease, but that generally do not respond well to drug treatment with levodopa. They are associated with abnormal protein buildup within brain cells.

The term refers to several conditions, each affecting particular parts of the brain and showing a characteristic course:

  • Dementia with Lewy bodies, characterized by an abnormal accumulation of alpha-synuclein protein in brain cells
  • Progressive supranuclear palsy, involving tau protein buildup affecting the frontal lobes, brainstem, cerebellum and substantia nigra
  • Multiple system atrophy, another synucleinopathy that affects the autonomic nervous system , substantia nigra and at times the cerebellum
  • Corticobasal syndrome, a rare tauopathy that typically affects one side of the body more than the other and makes it difficult for patients to see and navigate through space

Whats The Difference Between Multiple System Atrophy And Parkinsons

What is Parkinson

Parkinsons and MSA both affect the movement control system and the involuntary autonomic control system and early symptoms can make a differential diagnosis a challenge. MSA, however, tends to progress faster than Parkinsons balance problems and a stooped posture happen earlier and get worse more quickly with MSA and autonomic functions such as blood pressure, heart rate, breathing, sweating, bladder function, and sexual problems are more severe in people with MSA.

For more information on multiple symptom atrophy, read this fact sheet.

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Parkinson And Its Hallmark Symptoms

Parkinsons is a neurodegenerative disease that leads to shaking, stiffness, and difficulty with walking, and causes a person to lose control over some body functions.

Syndrome progresses gradually and differs from individual to individual. Parkinsons patients also experience mood swings accompanied by depression and anxiety.2

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No Dopamine Versus Disabled Dopamine

This is a condition that is almost close to Parkinsons disease. However, this resemblance is all based on principles.

This is Vaidya Pardeeps hard work and vision about Ayurveda. Importantly, only Sukhayu Ayurved, Jaipur is working on this approach and this is the reason we are able to help the patients with parkinsons disease. This is the first time in history of Ayurveda that someone has explained Parkinsons disease like this. With concept of Doshas and Gunas. And more importantly not using any substitute of dopamines for the Ayurvedic treatment for parkinsons disease.

This is like having money and your account is seized. Money is unreachable or you are blocked in any way. In such a condition- you need to make sure- you can utilize the money. Therefore the line of treatment will be different. And when you dont have any money, you need to earn more.

The same applies to Dopamine. Once receptors, where dopamine attaches, are blocked, you need to open these. And where dopamines are in low quantity, we need to improve and increase the production of the same.

Surgery For People With Parkinsons Disease

What is Parkinson’s Disease?

Deep brain stimulation surgery is an option to treat Parkinsons disease symptoms, but it is not suitable for everyone. There are strict criteria and guidelines on who can be a candidate for surgery, and this is something that only your doctor and you can decide. Surgery may be considered early or late in the progression of Parkinsons. When performing deep-brain stimulation surgery, the surgeon places an electrode in the part of the brain most effected by Parkinsons disease. Electrical impulses are introduced to the brain, which has the effect of normalising the brains electrical activity reducing the symptoms of Parkinsons disease. The electrical impulse is introduced using a pacemaker-like device called a stimulator. Thalamotomy and pallidotomy are operations where the surgeon makes an incision on part of the brain. These surgeries aim to alleviate some forms of tremor or unusual movement, but they are rarely performed now.

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Alzheimers And Parkinsons Disease: Similarities And Differences

James M. Ellison, MD, MPH

Swank Center for Memory Care and Geriatric Consultation, ChristianaCare Configure

  • Expert Advice

Explore the similarities and differences between two common degenerative brain disorders.

Ron brings his 78-year-old wife, Sara, to the Memory Clinic, with a pressing concern. Sara is forgetting things more often even though her Parkinsons disease symptoms appear to be under good control with standard medications, healthy diet, and plenty of physical activity. She is losing her train of thought mid-sentence and she became very confused about where she was while driving the well-traveled route to her daughters home. Is she developing dementia? Is that a part of Parkinsons disease? Or is she developing Alzheimers disease? And what are the differences between Alzheimers and Parkinsons?

Whats The Difference Between Dementia With Lewy Bodies And Parkinsons

In dementia with Lewy bodies, dementia always appears first. There can also be changes in alertness as well as visual hallucinations. However, because of the presence of Lewy bodies throughout the entire brain, characteristics of this disease not only include cognitive characteristics, but also physical, sleep, and behavioral changes. As the disease progresses, the motor symptoms common to Parkinsons such as tremor, slowness, stiffness, and walking and balance problems will appear.

For more information on dementia with Lewy bodies, visit www.lbda.org.

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What Happens In Parkinsons Disease

Substantia nigra is a small part of the brain. These parts secrets a chemical- dopamine. Dopamine is a hormone and neurotransmitter. It is responsible for many activities in the brain and body. This is also synthesized in kidneys along with the brain and other tissues. But external dopamine, other than produced in the brain, cannot cross the blood-brain barrier. Therefore external source is of least use.

When this neurotransmitter is not efficient in working. It leads to the problem of Parkinsons disease.

This happens in two ways.

Firstly, when dopamine is not able to communicate with the neural cells. And secondly, when production of the dopamine is not good. In both conditions, dopamine is not able to work efficiently. This causes problems with the activities of the brain which control through dopamine.

Here we need to know a bit more about dopamine. So that we can understand activities of the dopamine in a better way. This will help us to find about the Ayurveda treatment for Parkinsons disease.

The Purpose Of Clinical Diagnosis

Blood test may help differentiate Parkinson

The diagnosis of the parkinsonian syndromes is entirely clinical, as at the present time no imaging, biochemical, or genetic tests definitively diagnose or separate the different diseases. Diagnosis relies on taking a complete medical history that includes timeline of symptoms, recognition of the important clinical signs, and consideration of the differential diagnoses. Individuals diagnostic acumen is substantially influenced by clinical experience, and even among movement disorder specialists, the clinical diagnosis can change over time because of emerging clinical signs.

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