Wednesday, September 21, 2022

What Can You Do To Prevent Parkinson’s Disease

Trouble Moving Or Walking

Can we prevent dyskinesia in Parkinson’s?

Do you feel stiff in your body, arms or legs? Have others noticed that your arms dont swing like they used to when you walk? Sometimes stiffness goes away as you move. If it does not, it can be a sign of Parkinson’s disease. An early sign might be stiffness or pain in your shoulder or hips. People sometimes say their feet seem stuck to the floor.

What is normal?If you have injured your arm or shoulder, you may not be able to use it as well until it is healed, or another illness like arthritis might cause the same symptom.

So What Does Nutrition Have To Do With Parkinsons

1. The neurotransmitter dopamine is made in the body from amino acids which are the building blocks of protein. Every time we eat a protein rich food we take in protein, which the body breaks down into its component amino acids. Two amino acids are converted in the body into L-Dopa, which is then converted into dopamine in the brain.

2. Nutrient co-factors are required for each stage of this conversion process, so deficiencies of these may reduce dopamine production.

3. L-dopa medication competes for absorption with dietary amino acids, therefore the timing of taking L-dopa and the eating of protein needs to be managed for optimal absorption and effectiveness of the drug and the reduction of side-effects.

Therefore, the nutritional therapy approach to Parkinsons includes:

1. Supporting dopamine production by ensuring adequate precursors and co-factors

2. Considering drug-nutrient interactions to enhance effectiveness and reduce side-effects

3. Optimising nutritional status and addressing co-morbidities . These co-morbidities include constipation, depression, fatigue, and insomnia.

Physical Exercise Can Reduce Inflammation And Oxidative Stress

Accumulation of the -syn protein in neurons leads to inflammation in the brain . Aggregation of -Syn induced the production of proinflammatory cytokines, which are toxic and thus cause cell death of dopaminergic neurons . Therefore, reducing the inflammatory response may be an effective way to deal with PD. Several studies found that physical exercise can improve the oxidative metabolism and the expression of antioxidant enzymes in the brain of mice . Tuon et al. indicated that physical exercise was beneficial in reducing the production of proinflammatory proteins and inflammation in the brain of PD mice . This result is consistent with previous studies by Sung et al. and Al-Jarrah et al., which suggested that physical exercise could decrease the level of proinflammatory proteins in the striatum and hippocampus in the PD experimental model through reducing the activity of microglia .

Based on the above studies, we speculate that multiple pathways are involved in the regulation of physical exercise in PD animal experiments, such as alleviate the production of proinflammatory factors in the musculoskeletal muscle, reduce the expression of inflammatory factors in the brain, reduce the inflammatory response, and regulate oxidative stress .

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Stages Of Parkinsons Disease

Neurologists usually describe the progression of Parkinsons symptoms in stages, using the system known as the Hoehn and Yahr scale. These stages are:

  • Stage I Symptoms are seen on one side of the body only.
  • Stage II Symptoms are seen on both sides of the body. Theres no impairment of balance.
  • Stage III Balance impairment has begun. In this mild- to moderate stage of the disease, the person is still physically independent.
  • Stage IV This stage is marked by severe disability, but the person is still able to walk or stand unassisted.
  • Stage V The person is wheelchair-bound or bedridden unless assisted.

How To Prevent Parkinsons Disease With Diet And Lifestyle

How to Prevent Parkinson

The number of people diagnosed with Parkinsons disease and living with this condition is on the rise, with researchers estimating that over 1 million Americans will have this devastating illness by 2020.

Unfortunately, the conventional treatments available for Parkinsons disease are limited to surgical interventions and medications that come with numerous side effects. But a growing body of research indicates that there are many modifiable risk factors associated with the condition, providing us with clues as to what measures we can take to prevent the onset of the disease. Read on to learn how to prevent Parkinsons disease by using evidence-based dietary and lifestyle interventions.

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What Is Parkinsonism Is It Different From Parkinsons

Parkinsons disease is the most common cause of parkinsonism, a category of neurological diseases that cause slowed movement.

No quick or easy diagnostic tests exist for Parkinsons disease, so a patient may receive an initial diagnosis of parkinsonism without a more specific condition being confirmed.

Classic Parkinsons disease referred to as idiopathic because it has no known cause is the most common and most treatable parkinsonism.

About 15 percent of people with parkinsonism have atypical variants, which are also known as Parkinsons plus syndromes.

Home Remedyfor Parkinsons #8 Green Tea:

Green tea contains theanine, a nutrient that increasesdopamine levels in the brain, and polyphenol antioxidants that help fight free radicals. Three separate studies all found that regularlydrinking tea can either delay or prevent the development of PD. A retrospectivestudy also found that drinking three or more cups of tea a day can delay the onsetof motor symptoms. And a 2007 study found that green tea polyphenols protect braincells and dopamine neurons, and this positive effect increases with the moregreen tea consumed. 10

The minimum amount that should be drank every day is 3cups, with 6-9 cups a day being the ideal.Matcha green tea is the most potent and beneficial so try and purchase this ifyou can. A strong cup of coffee first thing in the morning is thought tobe effective for reducing the symptoms of Parkinsons disease as well, however,we recommend you stick with green tea, or even a strong cup of black tea ifyou can for the theanine and EGCGs.

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Tests To Rule Out Other Conditions

Blood tests can help rule out other possible causes of the symptoms, such as abnormal thyroid hormone levels or liver damage.

An MRI or CT scan can check for signs of a stroke or brain tumor, which may cause similar symptoms.

Hydrocephalus due to atrophy can occur with some types of dementia and would be visible with one of these imaging tests. If the person has neurologic symptoms but a normal scan result, Parkinsons disease may be present.

The doctor a lumbar puncture to rule out inflammation or a brain infection.

Production Of Dopamine Neurons From Stem Cells: Could We Be One Step Closer To The Cure

How to Avoid / Prevent Parkinson’s Dyskinesia

As the disease progresses, people may experience reduced quality of life, if normal functions such as swallowing, start to be affected. Currently, there is no known cure for Parkinsons disease. Once Parkinsons is diagnosed, the symptoms can often be treated with medications and therapies, especially in the early stages. However, the scientific community is making every effort to find a way to cure or at the very least find more effective ways to lessen the symptoms of this physically impairing disease.

As we mentioned before, the disease primarily affects dopamine-producing brain cells or neurons. The good news is, scientists in Sweden have identified some insights and a set of markers that should help control the quality of stem cells engineered for clinical use to treat Parkinsons disease. As the disease progresses and dopamine-producing brain cells malfunction and die, it leads to lower levels of dopamine, which is a chemical messenger essential for controlling movement. These findings should help fine-tune stem cell engineering to produce pure populations of high-quality dopamine neurons. Then, a pool of progenitor cells can be transplanted into the brains of patients, so they can make new supplies of dopamine cells.

But while this exciting new research is still in the lab, what else can we hope for to delay the symptoms of Parkinsons and improve the quality of life of those suffering from the disease?

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What Is The Outlook For Persons With Parkinsons Disease

Although there is no cure or absolute evidence of ways to prevent Parkinsons disease, scientists are working hard to learn more about the disease and find innovative ways to better manage it, prevent it from progressing and ultimately curing it.

Currently, you and your healthcare teams efforts are focused on medical management of your symptoms along with general health and lifestyle improvement recommendations . By identifying individual symptoms and adjusting the course of action based on changes in symptoms, most people with Parkinsons disease can live fulfilling lives.

The future is hopeful. Some of the research underway includes:

  • Using stem cells to produce new neurons, which would produce dopamine.
  • Producing a dopamine-producing enzyme that is delivered to a gene in the brain that controls movement.
  • Using a naturally occurring human protein glial cell-line derived neurotrophic factor, GDNF to protect dopamine-releasing nerve cells.

Many other investigations are underway too. Much has been learned, much progress has been made and additional discoveries are likely to come.

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Living With Parkinson Disease

These measures can help you live well with Parkinson disease:

  • An exercise routine can help keep muscles flexible and mobile. Exercise also releases natural brain chemicals that can improve emotional well-being.
  • High protein meals can benefit your brain chemistry
  • Physical, occupational, and speech therapy can help your ability to care for yourself and communicate with others
  • If you or your family has questions about Parkinson disease, want information about treatment, or need to find support, you can contact the American Parkinson Disease Association.

Natural Remedies And Treatments For Parkinsons Disease That Get Powerful Results

Understanding Parkinsonâs Disease

To successfully treat the symptoms of Parkinsons, andeven reverse this disorder, there are 4 things you must do

a) Increase your natural dopamine levels

b) Detox your body of all heavy metals andpollutants

c) Reduce all inflammation in the body,especially the brain

d) Repair the neuro pathways

These 10 natural treatments and remedies do all four. Solets not waste any more time then. Here they are in order of importance

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Exercise Helps Prevent Fight Parkinson’s Disease From The Harvard Health Letter

Parkinson’s is a brain disease that affects the body and how it moves. Early symptoms include tremors, a shuffling gait, and an overall slowing of physical movement. Yet exercise may be one of the best and most underutilized ways of combating the condition, according to the March 2012 .

Several prospective studies that followed tens of thousands of people for many years have shown a correlation between exercise earlier in life and a reduced chance of developing Parkinson’s later on. Exercising in your 30s and 40s decades before Parkinson’s typically occurs may reduce the risk of getting Parkinson’s disease by about 30%, notes the Health Letter. Some experts believe the exercise must be vigorous to make a difference. However, because this kind of research can’t prove cause and effect, there is the possibility of “reverse causation”: that is, exercise may not prevent Parkinson’s disease, but instead a very early “preclinical” form of the disease, without clear symptoms, may make people less willing or able to exercise in the first place.

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If You Have Parkinson’s Disease

If you have been diagnosed with Parkinson’s, call your doctor if:

  • You notice any significant change in your symptoms, such as severe episodes of freezingâa sudden loss of mobilityâwhich may affect walking.
  • Your response to your medicine changes.
  • Any other symptoms occur, such as constipation, sexual problems, or incontinence.
  • You have symptoms of depression, such as feeling sad or hopeless and losing interest in daily activities.
  • You or your family notice that you have problems with memory and thinking ability.

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Surgery And Deep Brain Stimulation

Deep brain stimulation is a treatment for Parkinsonâs disease that uses an implantable pacemaker-like device to deliver electrical pulses to parts of the brain involved in movement. The DBS system consists of leads precisely inserted into a specific brain target, the neurostimulator implanted in the chest, and extension wires that connect the leads to the neurostimulator. Though implantation of the system requires a neurosurgical procedure, the treatment itself consists of long-term electrical stimulation. Advantages of DBS include its ability to reduce the high doses of medications , its adjustability , and its reversibility DBS was approved by the Food and Drug Administration as a treatment for PD in 2002 and according to Medtronic , more than 80,000 patients have undergone DBS surgery worldwide.

Typical candidates are those who have motor fluctuations or periods of âoffâ time with troublesome symptoms alternating with periods of âonâ time with good symptom control, and also with possible periods of excessive movement .

Not all patients with Parkinsonâs disease are good candidates for treatment with DBS. Approximately 10â20% of patients considered for possible treatment with DBS include those:

How Is Parkinson’s Diagnosed

How can we cure Parkinson’s?

There are no tests that show that you have Parkinson’s. Your doctor will base a diagnosis on your symptoms, medical history and a detailed physical examination.

They will ask about your symptoms. They may also ask you to do some simple mental or physical tasks, such as moving or walking around.

It can be hard to diagnose Parkinsons in the early stages because symptoms are usually mild at first. If your doctor thinks you might have Parkinson’s, they will refer you to a specialist. This will usually be a neurologist or a geriatrician .

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Physical Activity Can Reduce The Risks Of Parkinson’s Disease

Physical activity plays an active role in the prevention and treatment of PD. The relationship between physical activity and risk of PD was first reported in the Nurses’ Health Study and HPFS, and later in five other longitudinal studies . The results of prospective epidemiological studies suggest that active physical activity reduces the risk of PD in men, but the mechanism is uncertain . There is no strong supporting evidence for the hypothesis that physical activity can prevent male PD in the Harvard Alumni Health Study. Nevertheless, a smaller sample size study shows a negative and nonsignificant association between physical activity and PD . A study of 143,325 participants from CPS-II-N has found that vigorous activity was associated with PD in men and women, while a reduction in PD risk through moderate to vigorous activity . The study of 213,701 participants of NIH-AARP Diet and Health Study cohort also confirmed this view that higher levels of moderate to vigorous activities at ages 35-39 or in the past ten years as reported in 1996-1997 were associated with low PD incidence after 2000, which was with a significant dose-response relationship. Compared to individuals who were inactive during the two periods, the risk of PD reduced by approximately 40% in the further analysis . Another study from the Swedish National March cohort showed that the total amount of daily activity was associated with a lower risk of PD, but women’s correlation was not apparent to men .

Causes And Risk Factors Of Parkinsons Disease

Most cases of Parkinsons disease are idiopathic, meaning the cause is unclear.

Its widely believed that a person with Parkinsons may have been genetically vulnerable to the disease, and that one or more unknown factors in the environment eventually triggered the disease.

Most of the symptoms of Parkinsons disease come from the loss of neurons in an area of your brain called the substantia nigra.

Normally, the neurons in this part of the brain make the chemical messenger dopamine, which allows communication with another area of the brain, the corpus striatum.

This communication helps produce smooth, purposeful movement. When the neurons in the substantia nigra die, the resulting loss of communication leads to the motor symptoms of Parkinsons.

Although the cause of this cell death is unknown, many researchers believe that the cells are killed by clumped proteins called Lewy bodies.

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Can Parkinsons Disease Be Prevented

Unfortunately, no. Parkinsons disease is long-term disease that worsens over time. Although there is no way to prevent or cure the disease , medications may significantly relieve your symptoms. In some patients especially those with later-stage disease, surgery to improve symptoms may be an option.

What Are The Different Stages Of Parkinsons Disease

Parkinson

Each person with Parkinsons disease experiences symptoms in in their own unique way. Not everyone experiences all symptoms of Parkinsons disease. You may not experience symptoms in the same order as others. Some people may have mild symptoms others may have intense symptoms. How quickly symptoms worsen also varies from individual to individual and is difficult to impossible to predict at the outset.

In general, the disease progresses from early stage to mid-stage to mid-late-stage to advanced stage. This is what typically occurs during each of these stages:

Early stage

Early symptoms of Parkinsons disease are usually mild and typically occur slowly and do not interfere with daily activities. Sometimes early symptoms are not easy to detect or you may think early symptoms are simply normal signs of aging. You may have fatigue or a general sense of uneasiness. You may feel a slight tremor or have difficulty standing.

Often, a family member or friend notices some of the subtle signs before you do. They may notice things like body stiffness or lack of normal movement slow or small handwriting, lack of expression in your face, or difficulty getting out of a chair.

Mid stage

Mid-late stage

Standing and walking are becoming more difficult and may require assistance with a walker. You may need full time help to continue to live at home.

Advanced stage

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