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Charlottes Web offers a scent that is light and pleasant, with notes of earth and pine. The taste of this bud delivers sweet notes of citrus and lemon with a woodsy base note.
Charlottes Web is named after a little girl named Charlotte Figi. Suffering from the rare condition Dravet Syndrome, Charlotte was suffering from about 300 seizures per month. Once she started consuming Charlottes Web, her seizures decreased to as low as four per month.
Because this Sativa strain contains less than 1% THC lacking psychoactive effects, Charlottes Web is considered an appealing all-natural therapy.
Bottom Line: Can Cbd Oil Help With Parkinsons Disease
Although Parkinsons has no cure, patients diagnosed with the condition can slow its progression and effectively manage its debilitating symptoms. One such way involves using CBD oil.
If youre planning to try out the health benefits of CBD oil on yourself, make sure to consult your plans with your doctor first. This will help you avoid potential side effects and drug interactions. A doctor expert on cannabis can also provide professional advice on finding the best dosage for your individual situation.
While more studies are needed to confirm the benefits of CBD oil for Parkinsons disease, you can always use it to support official treatment. When shopping for CBD oil online, remember to check the source of hemp, extraction method, and lab-testing practices used by the company to ensure youre getting a high-quality product that works.
Do you know someone who is taking CBD oil to manage Parkinsons disease? Let us know in the comments!
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Pathophysiology Of Parkinsons Disease
Pathologically, PD is characterized by early death of dopaminergic neurons in the SN pars compacta , leading to dopamine deficiency within the basal ganglia and a movement disorder consisting of the classic parkinsonian motor symptoms. However, PD is also associated with multiple non-motor symptoms, some of which precede motor dysfunction by more than a decade. The mainstay of PD management is symptomatic treatment with drugs that increase brain dopamine concentrations or directly stimulate dopamine receptors.
In this context, the search for more effective and tolerable treatments is imperative. Preclinical research provides opportunities for the discovery of new PD drugs, and animal models that mimic some aspects of PD have been used in an attempt to describe promising candidate agents. We searched MEDLINE for indexed articles published in English from inception to 2019. The following keywords were used: cannabis cannabidiol and neuroprotection endocannabinoids and basal ganglia Parkinsons animal models Parkinsons history Parkinsons and cannabidiol.
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Potential Risks Of Use
Studies on CBD have shown that this form of treatment is usually tolerated well by users and is regarded as safe. There has also been no evidence for potential of abuse and/or addiction. That said, a few undesirable side effects have been noted, which include diarrhea, appetite changes, and tiredness. In addition, there may be dangerous drug interactions when CBD is combined with certain pharmaceutical medications. And the FDA warns that CBD can cause liver injury . The agency also says that long-term side effects remain unknown. Therefore, it is crucial that one speak with his/her physician prior to adding CBD to any medication regimen. In addition, one should monitor side effects upon use.
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Endocannabinoids And Basal Ganglia
On the other hand, CB1 receptor activation dampens amphetamine-induced hyperlocomotion, as well as the rise in dopamine and glutamate release in the striatum.6868. Polissidis A, Chouliara O, Galanopoulos A, Naxakis G, Papahatjis D, Papadopoulou-Daifoti Z, et al. Cannabinoids negatively modulate striatal glutamate and dopamine release and behavioural output of acute D-amphetamine. Behav Brain Res. 2014 270:261-9. Striatal CB1 receptors also decrease GABAergic input to dopaminergic neurons of the SNpc, thus modulating the firing activity of these neurons.6969. Lovinger DM. Neurotransmitter roles in synaptic modulation, plasticity and learning in the dorsal striatum. Neuropharmacology. 2010 58:951-61. Accordingly, it has been accepted that the endocannabinoid system modifies striatal functioning and interferes with motor control.
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How Does Cbd Oil Help With Parkinsons Disease
Doctors may not use CBD oil for Parkinsons disease long-term, which is not surprising considering that research into the effects of CBD for this condition only started a few decades ago. Nevertheless, the current findings are very promising. Studies have found some positive effects of CBD on certain symptoms of Parkinsons disease, especially when it comes to non-motor symptoms, such as anxiety, depression, and insomnia.
Below we shed more light on the health benefits of CBD oil for Parkinsons disease patients.
Health Benefits For Medical Conditions
Charlottes Web provides a low-THC and high-CBD blend ideal for medicinal marijuana users who want the beneficial effects of cannabis while skipping the psychoactive high. This strain has been developed with medicinal patients in mind to help with their painful symptoms. Because there is barely any THC present in this strain, technically Charlottes Web can be consumed anytime, day or evening.
Improvement in the mood. There are many effects this weed strain provides, but one of the most common ones is an improvement in mood as a surge of energy and happiness washes over the mind and body.
Reducing anxiety. This high CBD flower is known to effectively reduce anxiety and even depression thanks to its uplifting and euphoric high.
Extensive medical benefits. Charlottes Web has proven its ability to aid medicinal patients with a myriad of ailments. These include epilepsy and seizures in children, chronic pain, muscle spasms, joint-related pains, and much more.
Neuropathic conditions. This cannabis strain may carry beneficial effects for individuals suffering from Parkinsons Disease, Fibromyalgia, and other neuropathic conditions.
Fatigue. If you are struggling with fatigue that is caused by a serious medical condition, Charlottes Web might be able to help ease the symptoms.
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How Is Parkinsons Disease Treated
Doctors usually recommend prescription medications to make the symptoms of Parkinsons disease manageable. Unfortunately, these medications only provide short-term relief and may require larger doses to produce the desired effects. This, in turn, may result in a range of side effects such as blurred vision, nausea, vomiting, diarrhea, heartburn, dry mouth, loss of appetite, drowsiness, lightheadedness, and more.
Lethal overdose is another serious risk of conventional treatments for Parkinsons disease.
Cbd Promotes Overall Wellness
Scientists have suggested that the many health benefits of CBD can lead to an improved quality of a persons life. This is a major problem for people diagnosed with Parkinsons disease, as it affects both physical and mental health to different degrees.
One study discovered that people with Parkinsons disease without psychiatric symptoms or conditions reported improved quality of life when taking CBD . However, this study involved a very small group of people, so further studies are needed to support the initial findings.
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Cbd Oil For Parkinsons
CBD oil can help in various health issues, significantly in pain and high blood pressure.
Preliminary research has found that CBD oil may help with treating quality of life issues in patients without psychotic symptoms. Another study showed the effectiveness of CBD in the treatment of psychosis in PD patients. The treatment did not worsen motor functions, and one of CBDs benefits was that it alleviated the psychotic symptoms present in the PD patients. There are clear advantages to using CBD oil for Parkinsons in the relief of non-movement related symptoms, not to mention it may have neuroprotective effects as part of the treatment.
While few studies exist as to CBDs potential benefits on movement disorder treatment in PD, clinical and pre-clinical research has shown a reversal of catalepsy in rodent models. And, dose-related improvement in dystonia was noted with CBD oil in five patients in an open-label study on movement disorders. The improvement ranged from 20% 50% in its effects on dystonia symptoms of Parkinson. More research is needed on CBDs effects on the nervous system in general and on the motor and non-motor symptoms, specifically in people with Parkinson.
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