Risks And Benefits For People With Pd
There are risks and benefits associated with the use of cannabis for people with PD. Benefits include a possible improvement in anxiety, pain management, sleep dysfunction, weight loss and nausea. Potential adverse effects include: impaired cognition , dizziness, blurred vision, mood and behavioral changes, loss of balance and hallucinations. Chronic use of marijuana can increase risk of mood disorders and lung cancer.
Benefits Of Cbd In Parkinsons Disease
Cannabidiol oil is manufactured by the dilution of CBD extracts with carrier oils such as hemp seed oil.
CBD is a cannabinoid obtained from Cannabis sativa and has the ability to modulate a variety of physiological responses by binding to specific receptors of the endocannabinoid system .
CBD is not psychoactive and has been proven to confer several health benefits.
Risks Does Cbd Have Any Side Effects
CBD is famous for having few side effects. Human studies and anecdotal reports have used dosages between 20 mg all the way up to 1.3 grams, without significant side effects. It is not yet known if it is possible to overdose on CBD . One of the more frequently reported side effects is sleepiness and lethargy from the anti-anxiety effect.
A more serious side effect is not the side effect of CBD but of medications, you take alongside CBD. CBD can inhibit liver metabolism leading to increased or decreased levels of many of the other drugs or supplements you are taking. Therefore, it is crucial that you ask your doctor about any drug interactions you might encounter with CBD. You should also research it yourself by using a pubmed.gov search. You cant leave everything up to your doctor. In the end, no one can take on the consequences of what you put in your body but you.
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Overview Of Parkinsons Disease
Parkinsons disease is a gradually degenerative disorder of the central nervous system . It mainly affects the motor system i.e., system concerned with movement.
The initial signs of the disorder include shaking, rigidity, and slowness of bodily movements. Patients also experience behavioural changes and encounter difficulties in thinking.
PD also leads to the development of anxiety and depression. Dementia is inevitable in the end stage of the disease.
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Parkinsons Disease And Its Diagnosis
James Parkinson, who discovered and described the symptoms of this disease at the beginning of the 19th century, is considered to be the creator of this disease. It is a disease of the nervous system, more precisely of its central part. Parkinsons disease is a neurodegenerative disease characterized by the progressive loss of nerve cells. This type of disease also includes Alzheimers disease, about which an entry has already been made on our blog. All interested parties are invited to explore this topic.
The Benefits And Research Around Cbd Are Still Emerging
With the legalization of medical marijuana, many states are approving the use of it in a non-traditional way to treat the symptoms of certain conditions, including Parkinsons disease. Marijuana has two major components to ittetrahydrocannabinol and cannabidiol . Both may help with nausea and muscle pain or spasms, but unlike THC, CBD doesnt give you the high feeling marijuana is most commonly known for. This makes it an enticing, natural way for many to help treat their Parkinsons disease symptoms. Whats more, is that because CBD is a natural compound from the Cannabis sativa plant, using it may also leave you side effect-free, unlike many prescription medications.
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How To Use Cbd Oil For Parkinsons Disease
Pay attention to your dosage in your use of CBD. It is recommended that you ask your health professional for medical advice, diagnosis, or treatment. Read the label on the bottle for dosage guidance or ask your health care professional for medical advice. It is always good to start with low doses and go slow, paying close attention to how you feel and at what dose your symptoms may improve without making things worse. In no time, you may experience an increase in your quality of life for the long term.
Sublingual Oils Vs Vapor Which Are Best
Looking at the comparison chart you can see the differences between these two popular delivery methods. CBD sublingual oils are taken by placing the desired amount of drops under the tongue and holding for 40-60 secs before swallowing. CBD Vapor is taken by puffing on a vaporizer pen with the desired CBD vaporizer cartridge.
Many people do not like vaping so the choice to use a sublingual oil is easy. Others may choose a vapor product over a sublingual oil because of the higher absorption rate, faster onset and convenience of carrying it on your person. Some prefer the sublingual oils because the effects last longer, it is easier to dial-in an exact dosage, and easier to take higher dosage servings. Many customers will opt to do both, using the sublingual oil for the main dose and a vape pen to supplement between doses. This is especially helpful for people tackling anxiety or chronic pain who may need to supplement throughout the day.
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How To Administer Cbd Oil For Parkinsons Disease
Commercial CBD oil may come in 30 ml bottles with a 1 ml dropper in it. The 30 ml vial concentration will differ, so if you have a 500-milligram bottle, each 1 ml dropper will contain 50 milligrams in one dropper-full of CBD. The label should have a table of contents indicating the dose per bottle and dropper.
For the fastest absorption and effects of CBD, squeeze the oil onto the back of the underside of your tongue for rapid absorption through the blood vessel located directly under the tongue. Most of the CBD bypasses the gastrointestinal tract, and this increases the rate of absorption.
The fastest absorption method is achieved with the use of vape pens. You may experience effects within minutes of using a vape pen. CBDs effects are noted within minutes of vaping.
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Cbd Vs Traditional Alzheimers Medications
As stated earlier, there is no cure for Parkinsonâs disease. This is unfortunate, but there are many pharmaceuticals available today that claim to help control the symptoms. Pharmaceuticals, by definition, are compounds that are manufactured specifically for medical use. A perfect example is Xanax, a popular pharmaceutical that is used to help treat tremors â but with terrible possible adverse side-effects:
- Sleepiness
- Hallucinations
- Insomnia
These pharmaceutical medications may not work the same for everyone â and those who do find relief may not have long-term success. This is because over time the body gradually builds a chemical tolerance, requiring stronger doses the longer the medication is used. Another potential issue is that the drug may eventually lose its effectiveness, which results in recurring symptoms.
How Parkinsons Disease Affects Your Brain
Weve already covered the macro-level concepts as it regards how Parkinsons works, but everyday consumers and researchers alike need to learn the underlying mechanisms involved in both a healthy and Parkinsons-affected brain in order to appreciate how therapeutic agents like cannabidiol can help.
How Your Brain Is Supposed to Work
The billions of nerve cells in your brain use cable-like extensions called axons to transmit impulses from one neuron to the next.
When an outgoing impulse or message reaches the end of an axon, it approaches a gap between the sending and receiving nerves known as the synapse.
The impulse is then ferried across the synapse by a specific chemical messenger, or neurotransmitterdopamine in this instance.
Once the dopamine accomplishes its job of getting the impulse across the synapse to the receiving neuron, it is broken down by enzymes.
How Your Brain Works with Parkinsons Disease
In the case of PD, the cells that produce dopamine die off for an unknown reason.
When the dopamine deficiency reaches 80 percent, the more readily recognizable symptoms of tremors and rigidity begin to manifest as communication between neurons is seriously impaired.
The immune system activates microglia in response to the rampant destruction of dopamine-producing cells microglia are a type of immune cell that cause inflammation and further damage to neurons when overstimulated.
How does cannabidiol counteract these harmful developments, you might be wondering?
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Forms Of Cbd Administration
There are a variety of options when it comes to administering CBD. Ingestible CBD, which is a very common means of consumption, and includes oils and tinctures . Sublingual consumption, whereby a few drops of oil or tincture is placed under the tongue for a few minutes, is often suggested because the oil is absorbed quickly into the bloodstream and is generally effective within a few minutes. One can also digest the oil or tincture directly or add to food, such as a smoothie. Oil capsules can be taken like pills. CBD edibles, like gummies, can take an hour before they start working. The effects can then be felt for 4 hours or even longer. Oils and tinctures can also be applied topically, meaning they can be applied to the skin. Like with digesting CBD, it can take an hour or so for the effects to be felt and will last for a few hours. This method of use is good for persons suffering from localized pain. One can also opt for CBD vape products , CBD inhalers, or smoke high-CBD hemp strains. This method of inhalation allows users to feel the effects of CBD almost immediately and generally lasts a couple of hours.
Did You Know?
There is no preferred method of CBD administration for persons with Parkinsons Disease. Patients should choose a method with which they are most comfortable and one which is not hampered by tremors. If success with CBD is found, users should choose an administration method which can accommodate frequent and ongoing usage.
Cbd As A Treatment For Parkinsons
CBD hasnt been used in people with Parkinsons disease long-term, and research into the benefits of this cannabinoid only began a few decades ago.
That means research is limited, and often, the studies that have been done are very small. Scientists and doctors need to conduct larger-scale efforts to confirm any benefits.
However, some studies suggest CBD may have some positive effects, especially when it comes to nonmotor symptoms, such as depression, anxiety, and sleep disorders.
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Treating Parkinsons Disease With Cbd Oil
Parkinsons disease is a neurodegenerative disorder that affects neurons in a specific area of the brain called substantia nigra. Due to the deterioration of this part of the brain, muscular movements are negatively impacted. The hallmark symptoms of Parkinsons disease include tremors, muscle rigidity or stiffness and postural instability. Most often, Parkinsons disease is accompanied by involuntary muscle movements and inability to control these movements. As the disease progresses, people with Parkinsons disease may also have mental and behavioral changes, sleep problems, depression, memory difficulties, and fatigue. Recent studies have indicated that there is a positive correlation between CBD and the management of symptoms brought about by Parkinsons disease.
Cbd Promotes Peaceful Sleep
About 96% of patients with Parkinsons disease suffer from several sleep-related disorders.
These disturbances, as evaluated by validated scales, such as the Parkinsons disease sleep scale usually reflect the severity of the disease.
The chief reasons behind the onset of sleep disturbances in PD have been categorized into four types.
The first reason for disturbed sleep is PD-related motor symptoms, such as nocturnal akinesia, early-morning dystonia , painful cramps, tremors, and difficulty turning in bed.
The next category is treatment-related nocturnal disturbances, particularly with drugs like levodopa and antidepressants.
Psychiatric symptoms like hallucinations, depression, dementia, vivid dreams, and psychosis can also disturb sleep in PD.
Finally, the presence of other sleep disorders like insomnia, restless leg syndrome, and rapid eye movement behavioural disorder can affect patients.
Sleep disorders can lead to new complications such as the development of anxiety disorders. They also increase stress levels and aggravate other symptoms of PD.
Rest is important for the patients as they are usually exhausted due to motor problems. CBD has a calming effect which helps in promoting sound sleep.
A 2017 review by the Palo Alto Health Care System acknowledged the potential of CBD in treating sleep-related disorders.
The review stated that CBD helps in promoting REM sleep and, thus, can help Parkinsons patients who are particularly affected due to REM sleep disruption.
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Final Thoughts On Using Cbd Oil For Parkinsons
There is no cure for Parkinsons disease. Once diagnosed, patients can only slow their progression.
However, there are ways to manage its pesky symptoms. One of them is using CBD oil. If youre planning to try it out, remember to make an appointment with your doctor first. This is to make sure that you dont experience any side effects of potential drug interactions. In addition, your doctor can also give you professional advice on finding the right dose.
Although more research is needed to confirm the benefits of CBD oil for Parkinsons disease, the best product that may support official treatment is Royal CBD oil. Made from organic hemp and using supercritical CO2, this product is pure, safe, and available in a wide range of potencies to suit different CBD needs.
Do you know anyone who takes CBD oil to cope with the symptoms of Parkinsons disease? Does it help? Let us know in the comment section below!
What Is Cbd Oil
CBD is a cannabinoid a naturally occurring chemical compound which can be extracted from the cannabis plant. It is then mixed with a carrier oil , to create CBD oil.
CBD is not psychoactive, like the better known TCH, which means that it wont make you high. CBD is legal across the UK, as long as it has been derived from an industrial hemp strain thats EU-approved.
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Possible Side Effects Of Cbd Oil
Most studies have concluded that CBD is a safe and well-tolerated substance. The WHO issued a complete report on the safety and efficacy of cannabidiol, supporting the earlier findings. CBD rarely causes any side effects, and if they do happen, they tend to be mild.
The side effects of CBD oil include:
- Dry mouth
- Fatigue
- Diarrhea
CBD can also interact with prescription and non-prescription medications, so make sure to always consult your doctor before taking CBD, especially if youre on medications that are metabolized by the Cytochrome P450 system. If your doctor tells you not to eat grapefruit along with your meds, the same rule applies to CBD because they use an identical mechanism, blocking the p450 system from metabolizing the active ingredients in those medications.