Our Natural Remedy To Cure Parkinsons Disease
Parkinsons disease is a progressive nervous system disorder that affects movement.
Parkinsons disease is the second most common neurodegenerative disorder after Alzheimers disease. Today, many laboratories and researchers are looking to improve the treatments already available to slow the progression of Parkinsons disease. They regularly offer new drugs ( levodopa , selegiline , azilectand new therapies. Unfortunately their treatments are often ineffective and they lead to disastrous side effects for the health of the patient. These drugs are unnecessary because they only fight the symptoms of Parkinsons disease, not the causes. If you have Parkinsons disease, or have a loved one who suffers from it, here is a natural, effective remedy without side effects that will allow you to cure the disease away from all those heavy chemical drugs. This natural treatment is the best for treating Parkinsons disease. It stands out because it is completely herbal and we see the patient and the family as a whole. Trust us ! It is the miracle solution to naturally cure Parkinsons disease.
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New Discovery May Lead To Effective Natural Treatment For Parkinsons Disease
Researchers working in Dr. Kwang-Soo Kims lab. Credit: McLean Hospital
Certain hormone-like compounds boost dopamine levels in the brain.
- The Nurr1 protein maintains the health of neurons that produce dopamine and die off during the progression of Parkinsons disease.
- Hormone-like compounds called prostaglandin A1 and E1 bind to and activate Nurr1.
- Prostaglandin A1 or E1 treatment lessened symptoms in a mouse model of Parkinsons disease.
Investigators have identified two molecules naturally produced by the body that stimulate the production of dopamine, the molecule that is in short supply in the brains of patients with Parkinsons disease. Stimulating dopamine production may help reverse the progression of the disease. The research was led by scientists at McLean Hospital in collaboration with scientists at Nanyang Technical University, Singapore, and published in the journal Nature Chemical Biology.
The team designed the study based on the knowledge that a protein called Nurr1 is key for maintaining the health of neurons that produce dopamine, which helps control a persons movements and emotions. It is thought that decreased Nurr1 effectiveness may lead to a decrease in dopamine levels, which then results in the development of Parkinsons disease.
How Soon After Treatment Will I Feel Better And How Long Will It Take To Recover
The time it takes to recover and see the effects of Parkinson’s disease treatments depends strongly on the type of treatments, the severity of the condition and other factors. Your healthcare provider is the best person to offer more information about what you can expect from treatment. The information they give you can consider any unique factors that might affect what you experience.
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When To Contact A Doctor
If you have a family history of Parkinsons disease, you may wish to talk with a doctor about your potential risks or even explore genetic testing. However, its important to remember that not all people with a family history of Parkinsons disease will be affected.
Signs of Parkinsons disease can be different for every person. Parkinsons is usually separated into premotor, motor, and cognitive stages. These dont necessarily occur in a particular order, and not everyone will experience them all.
As explained by the Parkinsons Foundation, common early symptoms include:
- tremor, or involuntary shaking of the hands
How Close Are We To A Cure For Parkinsons
Saskia Mair of Parkinsons Lifeinterviews Sohini Chowdhury, Deputy CEO of the Michael J Fox Foundation.
How close do you think the scientific community is to finding a cure for Parkinsons?
Whenever I say the word cure, I kind of put it in quotes. I think its important to remember that a cure can mean different things to different people.
If youre able to improve the symptom management of the disease to an extent where having the disease has very little impact on your day to day life, that could be considered a cure.
If youre able to slow or halt the disease progression so that the moment you get diagnosed, it never progresses beyond that point but youre still taking a pill every day for the rest of your life, that could be a cure.
Theres a recognition now that Parkinsons is not one disease experience. It is a disease experience that is very variable, so we have to be open minded because a cure for one person could be very different than a cure for another person.
I think the fact that this is now accepted in the research community is a good thing for patients. Its not a one size fit all approach. We have finally understood that we need lots of different cures to fit the different patient experiences under the name Parkinsons disease.
In terms of how close we are is it tomorrow? Absolutely not. But theres so many resources, money, scientific knowledge, and brainpower across the world being put forth into this.
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Myth : Parkinsons Is Only A Motor Condition
Fact: While its true that Parkinsons disease symptoms include shaking and tremor, rigid muscles, slowness of movement, and a frozen or flat expression, its a lot more than that.
Nonmotor symptoms deserve and are getting more attention from doctors and researchers. These symptoms include cognitive impairment or dementia , anxiety and depression, fatigue, sleep problems and more.
For some patients, nonmotor symptoms are more disabling than motor symptoms, which are the focus of treatment. Be sure to talk to your doctor about other issues so you can get all of your symptoms addressed.
Other Types Of Treatment For Parkinson’s Disease
Some people with Parkinson’s have surgery called deep brain stimulation . In this procedure, doctors place a wire deep inside a specific spot in the brain, depending on the symptoms that need treatment. DBS can lead to dramatic improvements in many people.
Scientists are also exploring ways to place cells that make dopamine into the brain to help treat people with Parkinson’s, instead of taking medicine. Some experts are trying to see if stem cells can be used for this, but research is still in an early stage.
Some treatments focus on the effects of the disorder, rather than the causes. Your doctor might refer you to a physical therapist to improve your balance and your ability to move. A physical therapist may also teach muscle-strengthening exercises to help you speak or swallow.
It’s important to keep up a daily exercise program and to stay socially active. You can get information about support groups and exercise classes in your area by checking with the American Parkinson Disease Association.
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How Can Stem Cell Technology Help
Stem cell technologies show promise for treating Parkinsons Disease and may play an increasing role in alleviating at least the motor symptoms, if not others, in the decades to come.
We are in desperate need of a better way of helping people with Parkinsons disease. It is on the increase worldwide. There is still no cure, and medications only go part way to fully treat incoordination and movement problems, said Claire Henchcliffe, from Weill Cornell Medical College in the US.
If successful, using stem cells as a source of transplantable dopamine-producing nerve cells could revolutionize care of the Parkinsons disease patient in the future, said Malin Parmar, from Lund University in Sweden.
A single surgery could potentially provide a transplant that would last throughout a patients lifespan, reducing or altogether avoiding the need for dopamine-based medications, said Parmar.
In the past, most transplantation studies in PD used human cells from aborted embryos. While these transplants could survive and function for many years, there were scientific and ethical issues foetal cells are in limited supply, and they are highly variable and hard to quality control.
Some patients were treated, while another developed allergy with the graft.
This approach is now rapidly moving into initial testing in clinical trials, researchers said.
The first systematic clinical transplantation trials using pluripotent stem cells as donor tissue were initiated in Japan in 2018.
What The Experiments Showed
Initially, the researchers tested the nanobody on mouse brain tissue in vitro. They found that PFFNB2 could bind to aggregates of alpha-synuclein, but could not prevent the formation of clumps.
Further experiments revealed that the nanobody could bind to and disrupt fibrils of alpha-synuclein that had already formed, destabilizing the misshapen proteins.
The researchers then tested this in live mice and found that the nanobody prevented alpha-synuclein from spreading to the cortex of the brain. The cortex is the largest part of the brain and is responsible for most higher brain functions.
Dr. Petrossian explained for MNT that he results showed that they were able to specifically target the preformed fibrils of alpha-synuclein in cell and mouse models, that they were able to reduce the clumping of alpha-synuclein in cell models, and they were able to reduce alpha-synuclein pathology in mouse models.
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Parkinsons Disease: Causes Symptoms And Treatments
Parkinsons disease is a brain disorder that causes unintended or uncontrollable movements, such as shaking, stiffness, and difficulty with balance and coordination.
Symptoms usually begin gradually and worsen over time. As the disease progresses, people may have difficulty walking and talking. They may also have mental and behavioral changes, sleep problems, depression, memory difficulties, and fatigue.
While virtually anyone could be at risk for developing Parkinsons, some research studies suggest this disease affects more men than women. Its unclear why, but studies are underway to understand factors that may increase a persons risk. One clear risk is age: Although most people with Parkinsons first develop the disease after age 60, about 5% to 10% experience onset before the age of 50. Early-onset forms of Parkinsons are often, but not always, inherited, and some forms have been linked to specific gene mutations.
How Does This Condition Affect My Body
Parkinsons disease causes a specific area of your brain, the basal ganglia, to deteriorate. As this area deteriorates, you lose the abilities those areas once controlled. Researchers have uncovered that Parkinsons disease causes a major shift in your brain chemistry.
Under normal circumstances, your brain uses chemicals known as neurotransmitters to control how your brain cells communicate with each other. When you have Parkinsons disease, you dont have enough dopamine, one of the most important neurotransmitters.
When your brain sends activation signals that tell your muscles to move, it fine-tunes your movements using cells that require dopamine. Thats why lack of dopamine causes the slowed movements and tremors symptoms of Parkinson’s disease.
As Parkinson’s disease progresses, the symptoms expand and intensify. Later stages of the disease often affect how your brain functions, causing dementia-like symptoms and depression.
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Whats Next For Tms And You
If youre a Parkinsons patient, the biggest question on your mind is whether transcranial magnetic therapy is right for you. Every patient is different, and what might work best for one patient might not work for you. Then again, it might. If you feel that your ongoing course of therapy isnt working, or your doctor, neurologist, or other healthcare provider has brought it up, you should bring up TMS therapy as a possibility. They may suggest a new course of medication or other therapy first, but it never hurts to ask about it. If nothing else, youll both be aware that there are options and alternatives that may provide a more satisfying and longer lasting period of reduced symptoms and diminished or eliminated side effects.
Dont be shy about bringing up TMS therapy for Parkinsons at your next doctor or neurologist visit. Your treatment is a working arrangement with your physicians, and you should all be willing to collaborate and share information during its course!
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The Surgical Option: Deep Brain Stimulation
Some patients with Parkinsons disease may benefit from deep brain stimulation , a surgical therapy that has been FDA approved for over a decade. DBS involves implanting an electrode into a targeted area of the brain, usually the subthalamic nucleus or the globus pallidus interna . The implants can be done on one side or both sides of the brain as needed. The electrodes are stimulated through a connection to a pacemaker-like device located under the skin in the chest. Patients that are considered good candidates for this procedure are those with a robust response to Levodopa, no significant cognitive or psychiatric problems, and no significant problems with balance. The procedure can help patients with medication-resistant tremors. It can also help patients who have significant motor fluctuations in which medication response varies during the day and dyskinesias or extra movements may occur as a side effect of medication.
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What Are The Different Stages Of Parkinsons Disease
Each person with Parkinsons disease experiences symptoms in in their own unique way. Not everyone experiences all symptoms of Parkinsons disease. You may not experience symptoms in the same order as others. Some people may have mild symptoms others may have intense symptoms. How quickly symptoms worsen also varies from individual to individual and is difficult to impossible to predict at the outset.
In general, the disease progresses from early stage to mid-stage to mid-late-stage to advanced stage. This is what typically occurs during each of these stages:
Early stage
Early symptoms of Parkinsons disease are usually mild and typically occur slowly and do not interfere with daily activities. Sometimes early symptoms are not easy to detect or you may think early symptoms are simply normal signs of aging. You may have fatigue or a general sense of uneasiness. You may feel a slight tremor or have difficulty standing.
Often, a family member or friend notices some of the subtle signs before you do. They may notice things like body stiffness or lack of normal movement slow or small handwriting, lack of expression in your face, or difficulty getting out of a chair.
Mid stage
Mid-late stage
Standing and walking are becoming more difficult and may require assistance with a walker. You may need full time help to continue to live at home.
Advanced stage
What Are Scientists Aiming To Achieve In The Near Future Through Research
This is an unbelievably robust time for Parkinsons research in that drug development and the therapeutic development pipeline is incredibly varied. I think thats whats really exciting.
At the Michael J Fox Foundation, we always say that the more shots on goal that you have, the greater the likelihood that something is going to get into that goal. Whats particularly interesting now is that all of those shots on goal are not the same approach and theyre not the same type of therapy.
The experience patients have with the disease is so variable. So the fact that we have all of these different approaches to trying to develop therapies gives a greater likelihood that we are going to come up with interventions to tackle these different parts of patient experiences. Its incredibly exciting to see not just researchers, but the biopharma sector and the investor community put resources into exploring all of these different approaches. Its not like everybody has their eggs in one basket were seeing a lot of different baskets, and thats potentially really beneficial for the patient community.
Sohini Chowdhury is deputy CEO at the Michael J Fox Foundation.
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Myth : Deep Brain Stimulation Is Experimental Therapy
Fact: Deep brain stimulation, or DBS, is a procedure in which doctors place electrodes in the brain at the point when medications are less effective in masking motor symptoms, such as tremor, stiffness and slowness of movement.
While it may sound frightening and futuristic, its been around and successfully used for decades. DBS works very similarly to a pacemaker, except the wire is in the brain, not in the heart. Its been a standard procedure for the past two decades.
Stages Of Parkinsons Disease
Neurologists usually describe the progression of Parkinsons symptoms in stages, using the system known as the Hoehn and Yahr scale. These stages are:
- Stage 1 Symptoms are seen on one side of the body only.
- Stage 2 Symptoms are seen on both sides of the body. Theres no impairment of balance.
- Stage 3 Balance impairment has begun. In this mild-to-moderate stage of the disease, the person is still physically independent.
- Stage 4 This stage is marked by severe disability, but the person is still able to walk or stand unassisted.
- Stage 5 The person requires a wheelchair or is bedridden unless assisted.
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Can Parkinsons Be Cured If Caught Early
Ernestine Wells | Answered August 6, 2021
Parkinsons disease cant be cured, but medications can help control the symptoms, often dramatically. In some more advanced cases, surgery may be advised. Your health care provider may also recommend lifestyle changes, especially ongoing aerobic exercise.Jul 8, 2022
Are Complementary Therapies Beneficial
Theres no simple answer to this. There are so many types of therapy that its impossible to generalise.
Theres evidence of the beneficial effect of some complementary therapies . For other therapies, there is no research to prove it has any benefits for people with Parkinsons. But we hear from many people affected who feel it helps them.
It will also depend on what you expect from complementary therapies. For example, you may feel a particular therapy is not having a positive effect on your Parkinsons symptoms, but you may enjoy the experience. For you, this might be enough of a reason to continue.
Weve included comments from people affected by Parkinsons who have tried some of the therapies. We hope this will give you a better idea of what people are trying and how they found it. But remember that everyone will have a different experience.
Please remember these are peoples personal opinions Parkinsons UK doesnt endorse any particular therapy.
People may use complementary therapies alongside prescribed medication for many reasons, for example:
- Conventional medicine might not always control someones symptoms.
- Complementary therapy is a way of taking control of your own health.
- Group therapy can be an opportunity to socialise. Equally, complementary therapies can be a time to enjoy your own company.
- Complementary therapies can be relaxing.
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