Naturalremedy For Parkinsons #7 Omega
Animal based omega-3 fatty acids are a powerful weapon inthe fight against Parkinsons disease. One of the main fatty acids, DHA, is oneof the essential building blocks for the human brain. Half of your brain andeyes are made up of fat and a large proportion of this is DHA fat.
Omega-3 fatty acids have the unique ability to cross theblood-brain barrier, something most conventional drugs cannot do. They helpincrease dopamine levels and reduce neuroinflammation in the brain, while atthe same time, stimulating neuron growth. So basically, EPA and DHA help preventbrain cell damage and keep the nervous system in tip top working order! 4
Best sources of animal based omega-3s are either fishoil, cod liver oil or krill oil. High strength krill oil is the preferred option as thiscontains a substance called Astaxanthin. Astaxanthin is a potent brain food nutrientthat has been shown to prevent neurodegeneration and inflammation of the brain.For dosages, take AT LEAST the highest recommended amount listed on the bottle the same goes with fish oil or cod liver oil. You cant overdose on thesesupplements so theres nothing to be concerned about. In fact, the more omega-3syou can get into you the better the results!
In addition to this, try and eat some cold water fattyfish such as salmon, tuna, mackerel, sardines or herring 3-4 times a week foran extra supply of DHA and EPA.
Improving The Performance Of Levodopa
Our bodies contain proteins that break down levodopa. This means, when levodopa enters the blood stream after been absorbed in the small intestine, much of the drug is deactivated before it even has the chance to get into the brain.
To counteract this, todays medications for Parkinsons combine levodopa with other drugs such as carbidopa and benserazide that block this break down, allowing more of the levodopa to get into the brain.
Levodopa was first combined with other drugs in the 1970s, and levodopa-carbidopa medications were made commercially available in 1975. Todays combination drugs mean lower doses of levodopa can be taken while still getting the same effect in the brain, which means fewer side effects and better symptom control.
But levodopa from Mucuna pruriens isnt combined with these levodopa enhancing drugs. So if you could take the same dose, less of the levodopa would get into the brain. And taking more to compensate for the break down would likely result in more side effects, such as nausea and constipation.
At the moment, there has been extremely limited research into the effectiveness and safety of Mucuna pruriens for people with Parkinsons. And on paper, it would seem that natural levodopa is unlikely to be as effective as, or replace, the medications that are already available. But could there be any benefits of natural levodopa?
Description Of The Screening Process
The detailed screening process was summarized in the PRISMA flow diagram . A total of 7,521 potentially relevant hits were initially yielded from the eight databases and other sources, in which 6,570 records were remained after removal of duplicates. Through screening titles and abstracts, we excluded 5,824 papers because they were studies with no relevance to PD , nonclinical trials , case reports, reviews, comments OR protocols . After full-text evaluation, 732 papers were excluded, including 234 that were not CHM studies, 142 that contained mixed interventions, 38 that aimed at single herb, herbal extracts or components, 305 that were not randomized double-blind placebo-controlled trials, and 13 that observed no outcome of interest. Ultimately, 14 eligible studies were selected in our study.
Figure 1. Flow diagram of the search process.
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Natural Remedies And Treatments For Parkinsons Disease That Get Powerful Results
To successfully treat the symptoms of Parkinsons, andeven reverse this disorder, there are 4 things you must do
a) Increase your natural dopamine levels
b) Detox your body of all heavy metals andpollutants
c) Reduce all inflammation in the body,especially the brain
d) Repair the neuro pathways
These 10 natural treatments and remedies do all four. Solets not waste any more time then. Here they are in order of importance
Natural Remedies And Treatments For Parkinsons Finalnote
So there you have our top 10 natural remedies andtreatments for reversing Parkinsons disease. We believe this is one of the most informative andthorough health articles on this disease youll find anywhere on the internet. Ifyou follow these 10 tips to-the-letter and continue to use them consistently,we guarantee that in 3-6 months time you will be truly astounded at themiraculous level of improvement youll see. In 12 months time you will scarcely recognize yourself! . But of course, you must stickwith them and follow through with each remedy every day if you want them towork. We sincerely hope you do.
Good luck and best wishes.
P.S. Because Parkinsons is closely linked to Alzheimers disease and actually goes under the dementia umbrella, we recommend you take the time to read our Powerful Natural Remedies for Dementia and Alzheimers article for a more complete and comprehensive understanding on the causes and treatments for these diseases. You can click on the link below to go there
Bioactive Molecules Derived From Parasitic Plants And Fungi
Cistanche salsa is a parasitic plant used as a Chinese traditional medicine containing acteoside, echinacoside, and tubuloside as its major phenylethanoid glycosides . C. salsa extracts containing these bioactive molecules have been shown to restore behavioral deficit and dopamine depletion in strata of MPTP induced C57 mice . They has also been demonstrated to protect dopaminergic neurons in the substantia nigra of PD model mice, which correlated with neurobehavior improvements and TH positive neuronal levels .
Gastrodia elata blume is a saprophytic perennial herb used traditionally as a medicine due to its wide range of therapeutic benefits. Protective effects of GE extract against MPP+-induced cytotoxicity in human dopaminergic SHSY-5Y cells demonstrated that GE extract dose dependently improved cell viability maintenance, attenuated oxidative damage, modulated expression of Bcl-2 and Bax, caspase-3, and limited poly polymerase proteolysis . Recently, MPP+ induced MN9D dopaminergic cells were shown to exhibit antiapoptotic effects following GE extract treatment. The v anillyl alcohol present in GE was considered to act by attenuating the MPP+ induced elevation of ROS levels and decreasing the Bax/Bcl-2 ratio and poly polymerase .
So What Does Nutrition Have To Do With Parkinsons
1. The neurotransmitter dopamine is made in the body from amino acids which are the building blocks of protein. Every time we eat a protein rich food we take in protein, which the body breaks down into its component amino acids. Two amino acids are converted in the body into L-Dopa, which is then converted into dopamine in the brain.
2. Nutrient co-factors are required for each stage of this conversion process, so deficiencies of these may reduce dopamine production.
3. L-dopa medication competes for absorption with dietary amino acids, therefore the timing of taking L-dopa and the eating of protein needs to be managed for optimal absorption and effectiveness of the drug and the reduction of side-effects.
Therefore, the nutritional therapy approach to Parkinsons includes:
1. Supporting dopamine production by ensuring adequate precursors and co-factors
2. Considering drug-nutrient interactions to enhance effectiveness and reduce side-effects
3. Optimising nutritional status and addressing co-morbidities . These co-morbidities include constipation, depression, fatigue, and insomnia.
Natural Remedies To Treat Parkinsons Disease
Natural Remedies to Treat Parkinsons Disease include taking fresh, raw fruits and vegetables, detoxifying the body, eating more probiotics, avoiding excessive iron, choosing and eating foods that promote good mood, consuming more vitamin Bs and magnesium, increasing the intake of Omega-3, taking green tea, and limiting the intake of protein.
Summary Of The Literature Cited
There are over 140 studies published in the last 10 years associated with the beneficial effects of plant- derived natural products and PD. This review included electronic searches of the PubMed, Medline, Scopus, EMBASE, CINAHL, AMED, PsycInfo, CNKI, 7 Korean Medical Databases, J-East and Web of Science with the search terms as follows: Parkinsons disease therapy, natural products parkinsons disease, phytochemicals, antioxidants and plant extracts in various combinations. The Dopamine and PD section is provided since the etiology of PD is thought to be due to an imbalance in brain dopamine levels. This review presents a summary of literature on the relationship between dopamine levels and motor function in PD, and the beneficial effects of natural products which demonstrate potential anti-PD properties. This also review summarizes recent progress in determining the potential mechanism of action on PD.
Foods That Are Hard To Chew
Many people with Parkinsons have difficulty with chewing and swallowing foods. A person needs medical help if this is the case. A speech and language therapist may be able to help a person overcome this issue.
However, if a person is finding certain foods hard to chew and swallow, they may wish to avoid these foods.
Such foods include:
- dry, crumbly foods
- tough or chewy meats
If a person does wish to eat chewy meats, they could try using gravy or sauce to soften them and make eating easier.
They could also try chopping meat into smaller pieces or incorporating meat into casseroles, which can make it more tender.
Having a drink with a meal can also make chewing and swallowing easier.
Optimise Your Diet Reduce Your Toxic Load
While the cause of Parkinsons is not known, environmental toxins such as pesticides and herbicides are implicated. Researchers have found levels of these chemicals to be higher in the brains of Parkinsons sufferers and incidence of Parkinsons is higher in areas with greater use of these chemicals. It makes sense to avoid any environmental toxins that you can. Also, consider your intake of dietary toxins such as alcohol and caffeine avoiding or reducing these may reduce the load on your bodys detoxification pathways.
A Lower Protein Diet To Help Meds Work Better
Your diet can impact how well your medication helps to manage common Parkinson’s symptoms, including tremors and constipation.
Diets heavy in protein, for instance, can limit your body’s absorption of levodopa in Sinemet, a common medication used in the management of Parkinson’s disease. As a result, some doctors recommend that people with Parkinson’s limit protein intake to 12 percent of their total daily calories. And taking your medication on an empty stomach before your meals can help your body absorb the drug, notes the Parkinson’s Disease Foundation.
The Michael J. Fox Foundation recommends avoiding certain foods because of possible medication interactions, including:
In addition, fruits and vegetables in your diet may protect nerve cell function and possibly help keep Parkinson’s symptoms under control. Fruits and veggies also provide fiber, which can stimulate bowel movement and prevent constipation. Ask your doctor for a referral to a nutritionist to help make it easier to follow a healthy diet.
Bump Up Your Fiber Intake
A high-fiber diet is a proven way to avoid constipation, a common problem for people with PD.
Parkinsons can slow down the intestines and cause constipation, Dr. Gostkowski says. Fiber helps keep things moving. There are plenty of high-fiber foods out there, so choose your favorites. Women should aim for 25 grams of fiber per day, and men should get 38 grams.
How Can It Help In Parkinson’s
The effects of herbal medicine in Parkinsons are largely untested with the exception of preliminary studies into Ayurveda – an ancient Indian healing system that combines a variety of interventions including herbal remedies.
Mucuna plants, which are used in Ayurveda herbal treatments, are known to contain levodopa – a key Parkinsons medication that increases dopamine levels in the brain and therefor improves the motor symptoms of the condition. Several studies into mucuna plants and Parkinsons have had positive results and some have even suggested that the plant might have advantages over conventional levodopa preparations in the long term management of Parkinsons. However, a rigorous clinical study into this is needed.
A qualified herbal practitioner will be able to advise on other remedies, for example nervine herbs to reduce tremors, or vascular dilators to relax rigid muscles. Some herbs may help with skin conditions.
But remember that natural does not mean harmless, and some herbal treatments can have serious side effects and interfere with Parkinsons medications. Always talk with your doctor before taking any herbal medicines.
New Treatment May Have The Potential To Slow Stop Or Reverse Parkinson Disease
Results from a recent study suggest that a revolutionary treatment may have the potential to slow, stop, or even reverse the progression of Parkinson disease.
Results from a February study of a revolutionary treatment suggest that it may be possible to slow, stop, or even reverse the progression of Parkinson disease, according to findings in the Journal of Parkinsons Disease.
The 3-part, experimental study investigated whether using a novel delivery system to increase levels of glial cell line-derived neurotrophic factor can regenerate dying dopamine brain cells in patients with Parkinson disease and even reverse their condition. GDNF is a naturally occurring protein that promotes the survival of many types of neurons.
I believe that this approach could be the first neuro-restorative treatment for people living with Parkinson’s, which is, of course, an extremely exciting prospect, Steven Gill, MB, MS, FRCS, who designed the infusion device used in the study, said in a statement.
Initially, 6 patients enrolled in a pilot study which evaluated the safety of the treatment approach. After the pilot study, 35 additional individuals participated in a subsequent 9-month double-blind trial. Half of the participants were randomly assigned to receive monthly infusions of GDNF while the other half received placebos.
Reference
New Discovery May Lead To Effective Natural Treatment For Parkinsons Disease
Researchers working in Dr. Kwang-Soo Kims lab. Credit: McLean Hospital
Certain hormone-like compounds boost dopamine levels in the brain.
- The Nurr1 protein maintains the health of neurons that produce dopamine and die off during the progression of Parkinsons disease.
- Hormone-like compounds called prostaglandin A1 and E1 bind to and activate Nurr1.
- Prostaglandin A1 or E1 treatment lessened symptoms in a mouse model of Parkinsons disease.
Investigators have identified two molecules naturally produced by the body that stimulate the production of dopamine, the molecule that is in short supply in the brains of patients with Parkinsons disease. Stimulating dopamine production may help reverse the progression of the disease. The research was led by scientists at McLean Hospital in collaboration with scientists at Nanyang Technical University, Singapore, and published in the journal Nature Chemical Biology.
The team designed the study based on the knowledge that a protein called Nurr1 is key for maintaining the health of neurons that produce dopamine, which helps control a persons movements and emotions. It is thought that decreased Nurr1 effectiveness may lead to a decrease in dopamine levels, which then results in the development of Parkinsons disease.
Eat More Fermented Foods As Probiotics
Beneficial bacteria are important to increase the level of gut flora that is often less fermented diets cause in our gut. Healthy gums highly important to prevent a host of diseases and disorders. Replenish your gut with beneficial bacteria and see the difference it makes in your overall health. This kind of bacteria can be attained from kombucha tea, kefir, kimchi, fermented soy , and sauerkraut. These edibles help the body detoxify heavy metals from it and break down environmental toxins in an efficient manner.
Foods Containing Saturated Fat And Cholesterol
Some studies suggest that dietary fat intake may increase the risk of Parkinsons.
Although having a higher intake of cholesterol can elevate a persons Parkinsons risk, having a higher intake of polyunsaturated fatty acids may reduce the risk.
Therefore, a person with Parkinsons may wish to reduce their intake of cholesterol to help control the symptoms of the condition. They may also wish to reduce the amount of saturated fat in their diet.
However, further studies are required to explore the link between dietary fat and Parkinsons.
Intake Of Fresh Raw Fruits And Vegetables
Fresh raw fruits and organic vegetables are widely known to provide all the necessary nutrients that cleanse your body. The nutrients include antioxidants, phytonutrients, enzymes, minerals, vitamins, flavonoids, amino acids, anti-inflammatory properties, and fiber. These nutrients are essential for digesting the food and consuming food void of these nutrients can cause a great deal of digestive and intestinal damage.
Neuroprotective Effects Of Ornamental Plants
Paeoniae lactiflora is an ornamental flowering plant known for its dried root. Paeoniflorin , a monoterpene glucoside, is abioactive molecule produced by Paeoniae alba Radix and is reported to have a neuroprotective effect on dopaminergic neurons in an MPTP mouse model for PD. Dose dependent subcutaneous administration of PF restored TH positive cells, dopaminergic neuronal paucity, and ameliorated bradykinesia. The mechanism of action is due to PF acting as an agonist for the adenosine A1 receptor, which down regulates microglial and astrocytic activation and neuroinflammation .
Dendrobium nobile Lindl. is an ornamental medicinal plant in the Orchidacea family, which is rich in the bioactive benzyl compound chrysotoxine .
Chrysotoxine is reported to protect SHSY-5Y cells against 6-OHDA toxicity through mitochondrial protection and NF-B modulation. Chrysotoxine pretreatment exerts beneficial effects including attenuation of 6-OHDA- induced intracellular generation of ROS, and activation of p38 MAPK and ERK1/2. Mitochondrial dysfunction is reverted through multiple mechanisms including the decrease of membrane potential, increase of intracellular free Ca2+, release of cytochrome c, imbalance of Bax/Bcl- 2 ratio and decrease in activation of caspase-3. An anti- inflammatory for response is exerted by suppression of NF- B activation by blocking its translocation to the nucleus, thereby preventing up-regulation of iNOS and intracellular NO release .
The Latest Research About Mucuna Pruriens As A Treatment For Parkinsons
In 2004, a study was conducted comparing the efficacy of MP with the standard medication used in PD, carbidopa/levodopa . Eight patients were given one dose of a MP preparation or C/L in a blinded fashion and then tested four hours after ingestion. MP acted more quickly and lasted longer than C/L without worsening of dyskinesias. A 2017 study also compared various single dose preparations of MP vs. C/L given blindly and determined that MP had a quicker onset of action, lasted longer and caused fewer dyskinesias.
However, when MP was given for longer periods of time as opposed to in single doses, the results were not as positive. In 2018, a study was conducted in which 14 patients were given MP powder for eight weeks and then carbidopa/levodopa for eight weeks. Seven of the patients discontinued MP, four for gastro-intestinal side effects and three for worsening of motor symptoms.
For the seven who remained on treatment, efficacy of MP was the same as C/L. Nobody discontinued during the C/L phase. Although the study showed that MP can be effective in reducing PD symptoms, it drew attention to the need for additional research into the optimal MP formulation and dose to allow for greater tolerability when taken continually.
H3: The difference between mucuna pruriens and cabidopa levodopa