George C Cotzias Fellowship Recipients
Here are the accomplishments of just a few of the past recipients of the George C. Cotzias Memorial Fellowship. :
Dr. David Eidelberg is the Susan and Leonard Feinstein Professor of Neurology and Neuroscience and has served as director of the Center for Neurosciences at the Feinstein Institutes for Medical Research in Manhasset, NY since its founding in 2001. His research focuses on characterizing the brain networks in PD and related disorders using imaging techniques, such as PET scanning and functional MRI.
Dr. David Standaert is the John N Whitaker Professor and Chair of Neurology at University of Alabama School of Medicine at Birmingham. His research focuses on understanding the molecular causes of PD including the role of inflammation in the development of PD. Dr. Standaert serves as the Chairman of APDAs Scientific Advisory Board.
Dr. Talene Yacoubian is an Associate Professor of Neurology at University of Alabama School of Medicine at Birmingham. Her research focuses on understanding the mechanisms that contribute to development of PD including the mechanisms by which abnormal alpha-synuclein propagates in the brain.
Dr. Vivek Unni is an Associate Professor of Neurology at Oregon Health & Science University in Portland, OR. His research focuses on understanding the role of alpha-synuclein in the development of PD using advanced imaging techniques in the live mouse brain.
Department Of Neurologyclinical Academic Building
About the department
The Department of Neurology faculty provides diagnostic and consultative services for all neurological disorders. The department serves as the major regional referral center for patients with movement disorders, including Parkinson’s disease, progressive supranuclear palsy and dystonia epilepsy stroke multiple sclerosis neurogenetic disorders neuromuscular disorders such as ALS and myasthenia gravis nervous systems disorders affecting vision such as optic neuritis headache and neurobehavioral disorders such as dementia.
to visit the department’s website.
Physicians & Professionals
Phone: Fax: 732-235-7041
The Cognitive and Behavioral Neurology Program at Robert Wood Johnson Medical School specializes in the evaluation, diagnosis and treatment of cognitive, psychiatric and behavioral syndromes within neurology. Conditions we treat include:
1. Diffuse and multifocal brain disorders affecting cognition and behavior .
2. Neurobehavioral syndromes associated with focal brain lesions .
3. Neuropsychiatric manifestations of neurological disorders .
Phone: Fax: 732-235-7041
Our Epilepsy Center consists of epilepsy neurologists, neurosurgeons, neuropsychologists, nurse practitioners, pharmacologists, psychiatrists, neuropathologist and research coordinators. We evaluate and manage new-onset or chronic seizure disorders.
Electrocorticography in assisting neurosurgeons for epilepsy resective surgery
What is ALS?
to download our program brochure.
Movement Disorders Treatment At Wake Forest Baptist
The Wake Forest Baptist Health Movement Disorders Center is the largest program of its kind in the Carolinas.
Movement and neurological disorders affect each patient differently. Your experience is unique, and so is your treatment. After meeting your doctors and undergoing a comprehensive evaluation, your multidisciplinary movement disorders team will meet with you to discuss your treatment options.
All of our physicians are specialists or subspecialists in their field they have dedicated their careers to diagnosing, treating and preventing movement disorders. Their experience and expertise mean you receive the nations highest quality of care for movement disorders.
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What Is The Psg Mentoring Committee
The PSG Mentoring Committee has three main roles.
1. To solicit, review, and select candidates to receive the Parkinsons Disease Foundation supported mentored clinical research award. This is a major award in support of a project that is a practical training ground for individuals to acquire new skills and expertise in clinical research.
1. To serve as a resource for individuals who need assistance in formulating and developing protocols to the point where they are ready for review by the Scientific Review Committee.
1. To develop and organize innovative programs to promote interest in Parkinsons disease research, facilitate the development of mentorship relationships, and increase awareness of resources within the PSG that can provide opportunities for initiating research efforts.
The Mentoring Committee oversees the PSG Advisor Program. Implemented in 2009, the PSG Advisor Program helps new investigators find a local mentor or specific research funding sources for their research.
Apda Helped Unlock The Mysteries Of Genes That Cause Parkinsons Disease
Up until the late 1980s, Parkinsons disease was understood to be caused mostly by environmental factors and not faulty genes.
There had been earlier studies which showed that clusters of PD existed in families, and doctors were aware that many of their patients reported PD in their families. However, in the 1980s it was understood that the reported clusters of PD in families actually reflected a variety of neurologic diseases that only resembled PD to the untrained eye, essential tremor for example.
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What Is The Parkinson Study Group
The Parkinson Study Group is a non-profit group of physicians and other health care providers from medical centers in the United States, Canada and Puerto Rico experienced in the care of Parkinson patients and dedicated to clinical research of Parkinson disease. The PSG was formed in 1986, prompted by the recognition that clinical research in Parkinson disease required the participation of large numbers of research patients under the cooperative care of skilled and experienced research physicians.
The PSG aims to advance knowledge about the cause, disease progression and treatment of PD and related disorders. The PSG is committed to:
- open communication within the scientific community
- ensuring research is peer reviewed by other health care providers prior to publication and that all research results are available to the public
- revealing potential conflicts of interest of the group and each PSG member and
- democratic governance of its organizations and activities.
Apdas Role In Genetic Research
Dr. Roger Duvoisin was one of the earliest chairmen of APDAs Scientific Advisory Board , and a prolific PD researcher. At the time, he worked at Robert Wood Johnson School of Medicine in New Jersey, which was, and continues to be, an APDA Center for Advanced Research. In the 1980s, he was involved in epidemiologic studies of sets of identical twins , one with PD and one without. In a paper published in 1983, 43 pairs of identical twins were studied, and only in one pair did both twins develop PD. This study further bolstered the conclusion that genetic factors didnot play a major role in the development of PD.
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About The American Parkinson Disease Association
The American Parkinson Disease Association is the largest grassroots network dedicated to fighting Parkinsons disease and works tirelessly to assist the more than 1 million Americans with PD live life to the fullest in the face of this chronic, neurological disorder. Founded in 1961, APDA has raised and invested more than $170 million to provide outstanding patient services and educational programs, elevate public awareness about the disease, and support research designed to unlock the mysteries of PD and ultimately put an end to this disease.
To join us in the fight against Parkinsons disease and to learn more about the support APDA provides nationally through our network ofChapters and Information & Referral Centers, as well as our national Research Program and Centers for Advanced Research, please visit us atwww.apdaparkinson.org.
I got this miracle shot, and I hope it helps other people like it helped me. Im blessed, lucky and grateful.
“I was in the hospital only two nights and am very pleased with the entire process.”
A 10-year-old girl collides with a bike, leading to emergency brain surgery.
The Genepd Study Funded By Apda
Dr. Duvoisin knew that other genes must be involved as well. He recruited his colleague and fellow APDA SAB member, Dr. Rick Myers, to this effort, who had just participated in the monumental achievement of identifying the genetic mutation in Huntingtons Disease. Dr. Myers worked at Boston University, another APDA Center for Advanced Research. APDAs SAB, then and now, is made up of preeminent PD researchers who worked at renowned PD centers all over the country.
Dr. Myers realized that he could draw on his relationships with APDAs SAB members to collaborate and collect families in which there were two or more first-degree relatives with PD. The study of these families was eventually known as the GenePD study, which was a multi-million dollar effort funded for decades by the National Institute of Neurological Disorders and Stroke to define the genetic determinants in PD.
APDA SAB members involved in this effort included: Dr. Lawrence Golbe , Dr. Robert Feldman , Dr. Ray Watts , Dr. G. Frederick Wooten , Dr. Erwin Montgomery , and Dr. John B. Penney .
The impressive stature of the members of this group encouraged others to join the study, which grew quickly to include non-APDA affiliated researchers as well: Dr. Mark Guttman , Dr. Oksana Suchowersky , Dr. Cheryl Waters , Dr. Jean Hubble , Dr. Carlos Singer , Dr. Mark Stacey , Dr. Christine Klein , Dr. Peter Pramstaller , and eventually to 25 sites internationally.
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Supporting The Work Of George C Cotzias Md
In 1957, Dr. Arvid Carlsson demonstrated that dopamine was a neurotransmitter, or brain chemical, that was important in movement. After these observations, doctors tried to treat people with PD with levodopa, a precursor of dopamine, that unlike dopamine was able to cross the blood brain barrier. These efforts were not successful, mostly because people could not tolerate the doses of levodopa required to improve movement. Doctors may have given up at that point if not for the crucial work of Dr. George C. Cotzias, who gave people small doses of levodopa every two hours, building up to the doses that were beneficial for movement. In this way, Dr. Cotzias demonstrated that levodopa was an effective and feasible treatment for Parkinsons disease.
Dr. Cotzias worked on many crucial elements of levodopa treatment. In this paper shown below, he made the critical observation of what is now called the levodopa protein effect, that in some people, diets high in protein can interfere with levodopa absorption and decrease the efficacy of the medication.
Although levodopa remains the most effective treatment for Parkinsons, research scientists have built upon the discoveries of Dr. Cotzias to devise a whole variety of new ways to deliver levodopa to the brains of people with PD. Read more about these formulations of levodopa
Facts About Parkinson’s Disease
It is incorrectly believed that Parkinson’s disease disappeared after the introduction of levodopa in the 1960s. In fact, about 50,000 Americans are newly diagnosed with Parkinson’s disease each year, with more than half a million Americans affected at any one time. Further, more people suffer from Parkinson’s disease than multiple sclerosis, muscular dystrophy and amyotrophic lateral sclerosis combined.
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Apda Center For Advanced Research
The RWJUH is home to one of eight Advanced Centers for Parkinson’s Research by the American Parkinson Disease Association. RWJUH research is focused on and is directed by a comprehensive team of experts. This Center is intended to strengthen and help integrate already existing investigative teams.
The funding of this Center supports a large research program, which includes: research trainees, fellowship programs early stage discovery programs and later stage clinical translation. The research is at the forefront of investigation into the causes, treatments and ultimately the cure for Parkinsons Disease.
Parkinson’s disease affects more than 1 million people in the United States annually, with at least 65,000 new cases diagnosed each year. The chronic and progressive neurological condition is the second most common neurodegenerative aging disorder, after Alzheimer’s disease.
Information on the most current Parkinson’s research
Lending library of videos, books and audiotapes on Parkinson’s disease
Annual symposium for patients and families
Newly diagnosed programs for patients and families
Annual Parkinson’s conference for healthcare providers
Support group training professionals
The Center For Neurosciences At Robert Wood Johnson University Hospital Hamilton
Experience a patient-centered approach to groundbreaking therapies and new surgical techniques with The Center for Neurosciences at Robert Wood Johnson University Hospital Hamilton.
The innovative team of neurosurgeons, subspecialty neurologists, and neuroscience researchers of Global Neurosciences Institute , coupled with the specialty-trained nurses, therapists, and other allied health professionals at RWJUH Hamilton, work together to provide a world-class, integrative, multidisciplinary approach to complete patient care.
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Ucsf Movement Disorders Fellowship
Training the next generation of leading academic movement disorders clinicians is the goal of our fellowship program at the UCSF Movement Disorders and Neuromodulation Center . Along with providing expert clinical care and innovative research, we view education as central to our mission of advancing the understanding and treatment of Parkinsons disease and other movement disorders. A spirit of collaboration is key to achieving these objectives and gives fellows a highly integrated, comprehensive, extraordinarily rich and varied training. From its inception, our program has benefited from partnerships with the San Francisco VA Parkinsons Disease and Research Education and Clinical Center and our internationally recognized integrated DBS/neurophysiology program . In recent years, this spirit of collaboration has expanded to our projects with the UCSF Memory and Aging Center. Dr. Caroline Tanner and others have built a leading research program in PD epidemiology and clinical trials. Our fellows get comprehensive training in design and conduct of clinical research.
What Is A Neuropsychology Evaluation
On the day of your evaluation, we will first discuss together the reason for your referral, your health history, and any symptoms you may be experiencing. Then you will be given a variety of testsusing both paper and pencil and a computerall administered in a face-to-face, one-on-one setting in a private, quiet room. You can take as many breaks as you need and ask any questions you have: you are in control of the process.
A typical neuropsychology visit takes about 3 to 4 hours, but may be shorter or longer depending on the complexity of your individual condition. A typical evaluation assesses:
- General intellect
- Mood and personality
But some abilities may be measured in more detail because of your specific needs.
Following your evaluation, we will prepare a comprehensive report. Our doctors will share this information with your referring physician and use it to develop your individualized treatment plan. We also provide the results directly to you, through a separate in-person visit. The report will include detailed analysis of your test results and comprehensive treatment plans and suggested intervention strategies as needed. We may also make suggestions for improving functioning and anticipating what your needs may be in the future.
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Other Symptoms Of Parkinson’s Disease
Symptoms of Parkinson’s disease vary from patient to patient. The symptoms may appear slowly and in no particular order. Early symptoms may be subtle and may progress over many years before reaching a point where they interfere with normal daily activities.These often include the following:
- Fatigue or general malaise
What Are The Four Primary Symptoms Of Parkinson’s
The following are the most common symptoms of Parkinson’s disease. However, each individual may experience symptoms differently. Symptoms may include:
- Rigidity Stiffness when the arm, leg or neck is moved back and forth.
- Resting Tremor Tremor most prominent at rest.
- Bradykinesia Slowness in initiating movement.
- Loss of Postural Reflexes Poor posture and balance that may cause falls gait or balance problems.
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Robert Wood Johnson University Hospital
One Robert Wood Johnson Place Phone:Hours:
Daily visiting hours are from 10 a.m. to 9 p.m.
Robert Wood Johnson University Hospital, one of the nation’s leading academic health centers, is the principal hospital for UMDNJ-Robert Wood Johnson Medical School and is home to the Heart Center of New Jersey, the Vascular Center of New Jersey, and central New Jersey’s only Level I Trauma Center.
Robert Wood Johnson University Hospital is a 965-bed hospital with campuses in New Brunswick and Somerville, offering Central New Jersey residents expanded access to the highest quality medical services and a wider array of innovative therapies available at only a small number of elite academic medical centers nationwide.
RWJUHs New Brunswick and Somerset campuses now serve as the flagship hospital of Robert Wood Johnson Health System, New Jerseys premier health system of choice which currently has $1.5 billion dollars in revenue, more than 10,100 employees, 3,250 medical staff members, and 1,733 beds.
RWJUH New Brunswick Community Resources
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Parkinson’s Syndrome Atypical Parkinson’s Or Parkinsonism
Parkinson’s disease is also called primary parkinsonism or idiopathic Parkinson’s disease. . In the other forms of parkinsonism, either the cause is known or suspected, or the disorder occurs as a secondary effect of another primary neurological disorder that may have both primary and secondary symptoms of Parkinson’s disease.
These disorders may include the following:
- Tumors in the brain
- Repeated head trauma
- Drug-induced parkinsonism – prolonged use of tranquilizing drugs, such as the phenothiazines, butyrophenones, reserpine, and the commonly used drug, metoclopramide for stomach upset
- Toxin-induced parkinsonism – manganese and carbon monoxide poisoning
- Postencephalitic parkinsonism – a viral disease that causes “sleeping sickness”
- Striatonigral degeneration – the substantia nigra of the brain is only mildly affected, while other areas of the brain show more severe damage
- Parkinsonism that accompanies other neurological conditions, such as :
- Shy-Drager syndrome
- Progressive supranuclear palsy
New Brunswick Neurologist Doctors And Specialists For Parkinson’s Disease
Type of Physician: Neurologist
What is a Neurologist? A certification by the Board of Psychiatry & Neurology practitioners focus on the diagnosis and treatment of all categories of disease or impaired function of the brain, spinal cord, muscles and nervous system, as well as the blood vessels that relate to these structures. The neurologist is often the primary physician but also serves as a consultant to other physicians and may render all levels of care, including the continuing care of outpatients and/or inpatients. The neurologist will often perform and interpret tests that relate to the nervous system or muscles.
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